Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics
Patient survival continues to increase with the growing quality of dialysis and management of chronic kidney disease (CKD). As such, chronic therapy must include considerations of quality of life (QOL), and this includes the disproportionate prevalence of sexual dysfunction (SD) in this patient popu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-04-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/11/4/311 |
| _version_ | 1827696098504867840 |
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| author | Jadzia Chou Thomas Kiebalo Piotr Jagiello Krzysztof Pawlaczyk |
| author_facet | Jadzia Chou Thomas Kiebalo Piotr Jagiello Krzysztof Pawlaczyk |
| author_sort | Jadzia Chou |
| collection | DOAJ |
| description | Patient survival continues to increase with the growing quality of dialysis and management of chronic kidney disease (CKD). As such, chronic therapy must include considerations of quality of life (QOL), and this includes the disproportionate prevalence of sexual dysfunction (SD) in this patient population. This review aims to describe the pathophysiological and the psychosocial causes of SD with regard to renal replacement therapy, particularly hemo- and peritoneal dialysis. The differences in its manifestation in men and women are compared, including hormonal imbalances—and therefore fertility, libido, and sexual satisfaction—the experience of depression and anxiety, and QOL. The impact of comorbidities and the iatrogenic causes of SD are described. This review also presents validated scales for screening and diagnosis of SD in CKD patients and outlines novel therapies and strategies for the effective management of SD. Increased prevalence of CKD invariably increases the number of patients with SD, and it is crucial for health care professional teams to become familiar with the clinical tools used to manage this sensitive and under-quantified field. As a known predictor of QOL, sexual function should become a point of focus in the pursuit of patient-centered care, particularly as we seek to achieve as “normal” a life as possible for individuals who receive dialysis. |
| first_indexed | 2024-03-10T12:39:08Z |
| format | Article |
| id | doaj.art-e3eccc2922af4025891395bdfbf55063 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-10T12:39:08Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-e3eccc2922af4025891395bdfbf550632023-11-21T14:03:07ZengMDPI AGLife2075-17292021-04-0111431110.3390/life11040311Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and TherapeuticsJadzia Chou0Thomas Kiebalo1Piotr Jagiello2Krzysztof Pawlaczyk3Department of Nephology, Transplantology and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Nephology, Transplantology and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Nephology, Transplantology and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Nephology, Transplantology and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, PolandPatient survival continues to increase with the growing quality of dialysis and management of chronic kidney disease (CKD). As such, chronic therapy must include considerations of quality of life (QOL), and this includes the disproportionate prevalence of sexual dysfunction (SD) in this patient population. This review aims to describe the pathophysiological and the psychosocial causes of SD with regard to renal replacement therapy, particularly hemo- and peritoneal dialysis. The differences in its manifestation in men and women are compared, including hormonal imbalances—and therefore fertility, libido, and sexual satisfaction—the experience of depression and anxiety, and QOL. The impact of comorbidities and the iatrogenic causes of SD are described. This review also presents validated scales for screening and diagnosis of SD in CKD patients and outlines novel therapies and strategies for the effective management of SD. Increased prevalence of CKD invariably increases the number of patients with SD, and it is crucial for health care professional teams to become familiar with the clinical tools used to manage this sensitive and under-quantified field. As a known predictor of QOL, sexual function should become a point of focus in the pursuit of patient-centered care, particularly as we seek to achieve as “normal” a life as possible for individuals who receive dialysis.https://www.mdpi.com/2075-1729/11/4/311renal replacement therapydialysisCKDsexual dysfunctionfertilityquality of life |
| spellingShingle | Jadzia Chou Thomas Kiebalo Piotr Jagiello Krzysztof Pawlaczyk Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics Life renal replacement therapy dialysis CKD sexual dysfunction fertility quality of life |
| title | Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics |
| title_full | Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics |
| title_fullStr | Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics |
| title_full_unstemmed | Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics |
| title_short | Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics |
| title_sort | multifaceted sexual dysfunction in dialyzing men and women pathophysiology diagnostics and therapeutics |
| topic | renal replacement therapy dialysis CKD sexual dysfunction fertility quality of life |
| url | https://www.mdpi.com/2075-1729/11/4/311 |
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