Evaluation of immunochromatographic assay in diagnosis of Giardia lamblia infection in comparison to Microscopy
Background: Giardia is recognized internationally as a most important etiology of persistent and chronic diarrhea especially in children with significant morbidity and mortality rates . Hence, rapid diagnosis is essential Objectives: To assess the diagnostic performance of Rida®Quick Giardia di...
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| Format: | Article |
| Language: | English |
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South Valley University, Faculty of Medicine
2024-01-01
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| Series: | SVU - International Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://svuijm.journals.ekb.eg/article_152419.html |
| _version_ | 1797255828471808000 |
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| author | Osama Hussein AbdEllah Alaa Mahmoud Rabie* Shamadan EzzEldeen Eman Abd El Azeem Asmaa M Elkady |
| author_facet | Osama Hussein AbdEllah Alaa Mahmoud Rabie* Shamadan EzzEldeen Eman Abd El Azeem Asmaa M Elkady |
| author_sort | Osama Hussein AbdEllah |
| collection | DOAJ |
| description | Background: Giardia is recognized internationally as a most important etiology of persistent and chronic diarrhea especially in children with significant morbidity and mortality rates . Hence, rapid diagnosis is essential
Objectives: To assess the diagnostic performance of Rida®Quick Giardia dipstick versus microscopy
Patients and Methods: A hundred fecal samples were collected from one hundred patients complaining of chronic diarrhea. All samples were investigated by Rida®Quick Giardia dipstick for coproa-antigen detection, and microscopically using concentration techniques
Results: The sensitivity, specificity, PPV, and NPV of Rida®Quick Giardia dipstick were 81.3%,96.3 %,95.1 % and84.9 respectively. There is no cross-reactivity with other intestinal parasites. Rida®Quick Giardia dipstick provide adequate sensitivity and specificity and give rapid results.
Conclusion: Rida®Quick Giardia is simple, rapid and has good sensitivity and specificity. Moreover, it does not require experienced personnel or special technical equipments. So, it can be used as an test in specific substitutional situations where the microscopic diagnosis of Giardia is limited due to time constraints, lack of microscopy experts, unavailability of appropriate equipments or when examining large populations as in outbreaks and epidemiological surveys |
| first_indexed | 2024-04-24T22:12:03Z |
| format | Article |
| id | doaj.art-e3f384f87fe84e16bcfc1edfb1a5be93 |
| institution | Directory Open Access Journal |
| issn | 2735-427X 2636-3402 |
| language | English |
| last_indexed | 2024-04-24T22:12:03Z |
| publishDate | 2024-01-01 |
| publisher | South Valley University, Faculty of Medicine |
| record_format | Article |
| series | SVU - International Journal of Medical Sciences |
| spelling | doaj.art-e3f384f87fe84e16bcfc1edfb1a5be932024-03-20T08:47:43ZengSouth Valley University, Faculty of MedicineSVU - International Journal of Medical Sciences2735-427X2636-34022024-01-0171317323https://doi.org/10.21608/svuijm.2021.64212.1095Evaluation of immunochromatographic assay in diagnosis of Giardia lamblia infection in comparison to MicroscopyOsama Hussein AbdEllah0Alaa Mahmoud Rabie*1Shamadan EzzEldeen2 Eman Abd El Azeem3 Asmaa M Elkady4Department of Medical Medical Parasitology , Faculty of Medicine, South Valley University, Qena, EgyptDepartment of Medical Medical Parasitology , Faculty of Medicine, South Valley University, Qena, EgyptDepartment of of Tropical Medicine and Gastroenterology , Faculty of Medicine, South Valley University,Qena, EgyptDepartment of Medical Medical Parasitology , Faculty of Medicine, South Valley University, Qena, EgyptDepartment of Medical Medical Parasitology , Faculty of Medicine, South Valley University, Qena, EgyptBackground: Giardia is recognized internationally as a most important etiology of persistent and chronic diarrhea especially in children with significant morbidity and mortality rates . Hence, rapid diagnosis is essential Objectives: To assess the diagnostic performance of Rida®Quick Giardia dipstick versus microscopy Patients and Methods: A hundred fecal samples were collected from one hundred patients complaining of chronic diarrhea. All samples were investigated by Rida®Quick Giardia dipstick for coproa-antigen detection, and microscopically using concentration techniques Results: The sensitivity, specificity, PPV, and NPV of Rida®Quick Giardia dipstick were 81.3%,96.3 %,95.1 % and84.9 respectively. There is no cross-reactivity with other intestinal parasites. Rida®Quick Giardia dipstick provide adequate sensitivity and specificity and give rapid results. Conclusion: Rida®Quick Giardia is simple, rapid and has good sensitivity and specificity. Moreover, it does not require experienced personnel or special technical equipments. So, it can be used as an test in specific substitutional situations where the microscopic diagnosis of Giardia is limited due to time constraints, lack of microscopy experts, unavailability of appropriate equipments or when examining large populations as in outbreaks and epidemiological surveyshttps://svuijm.journals.ekb.eg/article_152419.htmlgiardia lamblia immunochromatographic assay microscopy |
| spellingShingle | Osama Hussein AbdEllah Alaa Mahmoud Rabie* Shamadan EzzEldeen Eman Abd El Azeem Asmaa M Elkady Evaluation of immunochromatographic assay in diagnosis of Giardia lamblia infection in comparison to Microscopy SVU - International Journal of Medical Sciences giardia lamblia immunochromatographic assay microscopy |
| title | Evaluation of immunochromatographic assay in diagnosis of Giardia lamblia infection in comparison to Microscopy |
| title_full | Evaluation of immunochromatographic assay in diagnosis of Giardia lamblia infection in comparison to Microscopy |
| title_fullStr | Evaluation of immunochromatographic assay in diagnosis of Giardia lamblia infection in comparison to Microscopy |
| title_full_unstemmed | Evaluation of immunochromatographic assay in diagnosis of Giardia lamblia infection in comparison to Microscopy |
| title_short | Evaluation of immunochromatographic assay in diagnosis of Giardia lamblia infection in comparison to Microscopy |
| title_sort | evaluation of immunochromatographic assay in diagnosis of giardia lamblia infection in comparison to microscopy |
| topic | giardia lamblia immunochromatographic assay microscopy |
| url | https://svuijm.journals.ekb.eg/article_152419.html |
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