SPDEF drives pancreatic adenocarcinoma progression via transcriptional upregulation of S100A16 and activation of the PI3K/AKT signaling pathway

SPDEF drives pancreatic adenocarcinoma progression via transcriptional upregulation of S100A16 and activation of the PI3K/AKT signaling pathway

Pancreatic adenocarcinoma (PAAD) is a notably aggressive malignancy with limited treatment options and an unfavorable prognosis for patients. We aimed to investigate molecular mechanisms by which Sam's pointed domain-containing ETS transcription factor (SPDEF) exerts effects on PAAD progressio...

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Bibliographic Details
Main Authors: Hang Jiang, Zhiqian Xue, Liping Zhao, Boyuan Wang, Chenfei Wang, Haihan Song, Jianjun Sun
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2024-03-01
Series:Biomolecules & Biomedicine
Subjects:
Pancreatic adenocarcinoma (PAAD)
Sam's pointed domain-containing ETS transcription factor (SPDEF)
S100A16
PI3K/AKT signaling pathway
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/10346

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