Type II Peter’s anomaly with histopathological proof: a case report
Abstract Background Peter’s anomaly is a rare congenital anterior segment dysgenesis with poor visual results. This case report describes a case of bilateral Type II Peter’s anomaly with notable clinical and histopathological features. Case presentation A 7-year-old boy was admitted to our center wi...
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| Format: | Article |
| Language: | English |
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BMC
2017-06-01
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| Series: | BMC Ophthalmology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12886-017-0502-7 |
| _version_ | 1818152835794075648 |
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| author | Rui-Qi Chang Yu Du Xiang-Jia Zhu Yi Lu |
| author_facet | Rui-Qi Chang Yu Du Xiang-Jia Zhu Yi Lu |
| author_sort | Rui-Qi Chang |
| collection | DOAJ |
| description | Abstract Background Peter’s anomaly is a rare congenital anterior segment dysgenesis with poor visual results. This case report describes a case of bilateral Type II Peter’s anomaly with notable clinical and histopathological features. Case presentation A 7-year-old boy was admitted to our center with complaints of bilateral central opacification, photophobia and severe reduced vision since birth. He underwent phacoemulsification, intraocular lens (IOL) implantation and anterior vitrectomy on the right eye in another medical institution two years ago. Slit lamp examination revealed bilateral central corneal opacity, few strands of peripheral iris, irregular pupils and cloudy lens with central adhesion to posterior corneal surface in the left eye. Additionally, a history of premature birth and mental retardation was also noted. The patient was diagnosed with Peter’s anomaly in the left eye, pseudophakia in the right eye and bilateral amblyopia. Similar surgery to the right one was performed on the left eye. A vesicle-like structure was found in the anterior chamber intraoperatively, which was composed mainly of immature lens and some corneal stroma as revealed by postoperative histopathological examinations. Conclusions The exact mechanism of Peter’s anomaly is not completely understood, however, the notable histopathological features of tissue obtained from the present case may provide evidence to the hypothesis of developmental anomalies. |
| first_indexed | 2024-12-11T14:01:02Z |
| format | Article |
| id | doaj.art-e3f882ac718c4ffdab1e33bb36460350 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-11T14:01:02Z |
| publishDate | 2017-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-e3f882ac718c4ffdab1e33bb364603502022-12-22T01:03:51ZengBMCBMC Ophthalmology1471-24152017-06-011711510.1186/s12886-017-0502-7Type II Peter’s anomaly with histopathological proof: a case reportRui-Qi Chang0Yu Du1Xiang-Jia Zhu2Yi Lu3Department of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan UniversityDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan UniversityDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan UniversityDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan UniversityAbstract Background Peter’s anomaly is a rare congenital anterior segment dysgenesis with poor visual results. This case report describes a case of bilateral Type II Peter’s anomaly with notable clinical and histopathological features. Case presentation A 7-year-old boy was admitted to our center with complaints of bilateral central opacification, photophobia and severe reduced vision since birth. He underwent phacoemulsification, intraocular lens (IOL) implantation and anterior vitrectomy on the right eye in another medical institution two years ago. Slit lamp examination revealed bilateral central corneal opacity, few strands of peripheral iris, irregular pupils and cloudy lens with central adhesion to posterior corneal surface in the left eye. Additionally, a history of premature birth and mental retardation was also noted. The patient was diagnosed with Peter’s anomaly in the left eye, pseudophakia in the right eye and bilateral amblyopia. Similar surgery to the right one was performed on the left eye. A vesicle-like structure was found in the anterior chamber intraoperatively, which was composed mainly of immature lens and some corneal stroma as revealed by postoperative histopathological examinations. Conclusions The exact mechanism of Peter’s anomaly is not completely understood, however, the notable histopathological features of tissue obtained from the present case may provide evidence to the hypothesis of developmental anomalies.http://link.springer.com/article/10.1186/s12886-017-0502-7Peter’s anomalyCongenital cataractCorneal leukomaAmblyopiaHistopathologyCorneolenticular adhesion |
| spellingShingle | Rui-Qi Chang Yu Du Xiang-Jia Zhu Yi Lu Type II Peter’s anomaly with histopathological proof: a case report BMC Ophthalmology Peter’s anomaly Congenital cataract Corneal leukoma Amblyopia Histopathology Corneolenticular adhesion |
| title | Type II Peter’s anomaly with histopathological proof: a case report |
| title_full | Type II Peter’s anomaly with histopathological proof: a case report |
| title_fullStr | Type II Peter’s anomaly with histopathological proof: a case report |
| title_full_unstemmed | Type II Peter’s anomaly with histopathological proof: a case report |
| title_short | Type II Peter’s anomaly with histopathological proof: a case report |
| title_sort | type ii peter s anomaly with histopathological proof a case report |
| topic | Peter’s anomaly Congenital cataract Corneal leukoma Amblyopia Histopathology Corneolenticular adhesion |
| url | http://link.springer.com/article/10.1186/s12886-017-0502-7 |
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