Acute nicotine administration effects on fractional anisotropy of cerebral white matter and associated attention performance

Introduction.Nicotinic acetylcholine receptors are present in the cerebral white matter (WM). We hypothesized that WM response to nicotine can be detected by diffusion tensor imaging (DTI); and that such responses may be associated with nicotine-led cognitive enhancement in sustained attention. Meth...

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Bibliographic Details
Main Authors: Peter eKochunov, Michael eDu, Lauren eMoran, Hema eSampath, Andrea eWijtenburg, Yihong eYang, Laura M Rowland, Elliot eStein, Elliott eHong
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00117/full