Identification of <i>Cdk8</i> and <i>Cdkn2d</i> as New Prame-Target Genes in 2C-like Embryonic Stem Cells

Identification of <i>Cdk8</i> and <i>Cdkn2d</i> as New Prame-Target Genes in 2C-like Embryonic Stem Cells

Embryonic stem cells (ESCs) present a characteristic pluripotency heterogeneity correspondent to specific metastates. We recently demonstrated that retinoic acid (RA) induces an increase in a specific 2C-like metastate marked by target genes specific to the two-cell embryo stage in preimplantation....

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Bibliographic Details
Main Authors: Valeria Lucci, Elena De Marino, Daniela Tagliaferri, Stefano Amente, Alessandra Pollice, Viola Calabrò, Maria Vivo, Geppino Falco, Tiziana Angrisano
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Genes
Subjects:
PRAME
embryo stem cell
RA-resistant
Online Access:https://www.mdpi.com/2073-4425/13/10/1745

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