Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review
Atherosclerosis is still considered a disease burden with long-term damaging processes towards the cardiovascular system. Evaluation of atherosclerotic stages requires the use of independent markers such as those already considered traditional, that remain the main therapeutic target for patients wi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/12/3141 |
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| author | Gabriela Bordeianu Ivona Mitu Raluca Stefania Stanescu Corina Paraschiva Ciobanu Elena Petrescu-Danila Afrodita Doina Marculescu Daniela Cristina Dimitriu |
| author_facet | Gabriela Bordeianu Ivona Mitu Raluca Stefania Stanescu Corina Paraschiva Ciobanu Elena Petrescu-Danila Afrodita Doina Marculescu Daniela Cristina Dimitriu |
| author_sort | Gabriela Bordeianu |
| collection | DOAJ |
| description | Atherosclerosis is still considered a disease burden with long-term damaging processes towards the cardiovascular system. Evaluation of atherosclerotic stages requires the use of independent markers such as those already considered traditional, that remain the main therapeutic target for patients with atherosclerosis, together with emerging biomarkers. The challenge is finding models of predictive markers that are particularly tailored to detect and evaluate the evolution of incipient vascular lesions. Important advances have been made in this field, resulting in a more comprehensible and stronger linkage between the lipidic profile and the continuous inflammatory process. In this paper, we analysed the most recent data from the literature studying the molecular mechanisms of biomarkers and their involvement in the cascade of events that occur in the pathophysiology of atherosclerosis. |
| first_indexed | 2024-03-09T17:08:49Z |
| format | Article |
| id | doaj.art-e3fcf03c1ae649f4ba04fb6c2d849583 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T17:08:49Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-e3fcf03c1ae649f4ba04fb6c2d8495832023-11-24T14:19:23ZengMDPI AGDiagnostics2075-44182022-12-011212314110.3390/diagnostics12123141Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature ReviewGabriela Bordeianu0Ivona Mitu1Raluca Stefania Stanescu2Corina Paraschiva Ciobanu3Elena Petrescu-Danila4Afrodita Doina Marculescu5Daniela Cristina Dimitriu6Department of Morpho-Functional Sciences II, University of Medicine and Pharmacy “Grigore T. Popa”, 700115 Iasi, RomaniaDepartment of Morpho-Functional Sciences II, University of Medicine and Pharmacy “Grigore T. Popa”, 700115 Iasi, RomaniaDepartment of Morpho-Functional Sciences II, University of Medicine and Pharmacy “Grigore T. Popa”, 700115 Iasi, RomaniaDepartment of Morpho-Functional Sciences II, University of Medicine and Pharmacy “Grigore T. Popa”, 700115 Iasi, RomaniaDepartment of Morpho-Functional Sciences II, University of Medicine and Pharmacy “Grigore T. Popa”, 700115 Iasi, RomaniaDepartment of Morpho-Functional Sciences II, University of Medicine and Pharmacy “Grigore T. Popa”, 700115 Iasi, RomaniaDepartment of Morpho-Functional Sciences II, University of Medicine and Pharmacy “Grigore T. Popa”, 700115 Iasi, RomaniaAtherosclerosis is still considered a disease burden with long-term damaging processes towards the cardiovascular system. Evaluation of atherosclerotic stages requires the use of independent markers such as those already considered traditional, that remain the main therapeutic target for patients with atherosclerosis, together with emerging biomarkers. The challenge is finding models of predictive markers that are particularly tailored to detect and evaluate the evolution of incipient vascular lesions. Important advances have been made in this field, resulting in a more comprehensible and stronger linkage between the lipidic profile and the continuous inflammatory process. In this paper, we analysed the most recent data from the literature studying the molecular mechanisms of biomarkers and their involvement in the cascade of events that occur in the pathophysiology of atherosclerosis.https://www.mdpi.com/2075-4418/12/12/3141atherosclerosiscardiovascular diseaseceramidesrisk scores |
| spellingShingle | Gabriela Bordeianu Ivona Mitu Raluca Stefania Stanescu Corina Paraschiva Ciobanu Elena Petrescu-Danila Afrodita Doina Marculescu Daniela Cristina Dimitriu Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review Diagnostics atherosclerosis cardiovascular disease ceramides risk scores |
| title | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
| title_full | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
| title_fullStr | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
| title_full_unstemmed | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
| title_short | Circulating Biomarkers for Laboratory Diagnostics of Atherosclerosis—Literature Review |
| title_sort | circulating biomarkers for laboratory diagnostics of atherosclerosis literature review |
| topic | atherosclerosis cardiovascular disease ceramides risk scores |
| url | https://www.mdpi.com/2075-4418/12/12/3141 |
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