18F-FDG PET, contrast CT and MRI to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerve
We present a case of a 78-year-old male with a primary parotid squamous cell carcinoma which spread via the left facial, trigeminal and greater auricular nerves. The patient presented with left facial droop and paraesthesia. Initial MRI scans demonstrated involvement of the trigeminal and facial ner...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-06-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043322002552 |
| _version_ | 1818027533199736832 |
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| author | Manvinder Dhillon, BMedSci, MBBS, PGDAAD, MS Gavin Mackie, MBBS, FRANZCR, FAANMS Dalveer Singh, MBBS, FRANZCR, FAANMS |
| author_facet | Manvinder Dhillon, BMedSci, MBBS, PGDAAD, MS Gavin Mackie, MBBS, FRANZCR, FAANMS Dalveer Singh, MBBS, FRANZCR, FAANMS |
| author_sort | Manvinder Dhillon, BMedSci, MBBS, PGDAAD, MS |
| collection | DOAJ |
| description | We present a case of a 78-year-old male with a primary parotid squamous cell carcinoma which spread via the left facial, trigeminal and greater auricular nerves. The patient presented with left facial droop and paraesthesia. Initial MRI scans demonstrated involvement of the trigeminal and facial nerves with no sign of a primary lesion. Abnormal enhancement within the left parotid substance on FDG PET-CT demonstrated the primary malignancy which was confirmed on histology by core biopsy. There was also focal avidity along the course of the left greater auricular nerve consistent with perineural infiltration, extending from the posterior aspect of the parotid to the left cervical plexus at C2/C3. To our knowledge, this is the second case of squamous cell carcinoma perineural spread to the greater auricular nerve imaged on FDG PET-CT scanning. This case highlights the importance of multimodality imaging correlation in the workup of primary head and neck malignancies and associated perineural spread, which is essential in adjuvant radiation therapy planning to reduce local recurrence, improve prognosis and overall survival. |
| first_indexed | 2024-12-10T04:49:24Z |
| format | Article |
| id | doaj.art-e3ff468ef3914769a96704f91130b87c |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-10T04:49:24Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-e3ff468ef3914769a96704f91130b87c2022-12-22T02:01:40ZengElsevierRadiology Case Reports1930-04332022-06-011762106211018F-FDG PET, contrast CT and MRI to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerveManvinder Dhillon, BMedSci, MBBS, PGDAAD, MS0Gavin Mackie, MBBS, FRANZCR, FAANMS1Dalveer Singh, MBBS, FRANZCR, FAANMS2School of Medicine, University of Queensland, Herston, QLD 4006, AustraliaQscan Radiology Clinics, Hobart, TAS 7000, AustraliaSchool of Medicine, University of Queensland, Herston, QLD 4006, Australia; Qscan Radiology Clinics, Hobart, TAS 7000, Australia; Corresponding author.We present a case of a 78-year-old male with a primary parotid squamous cell carcinoma which spread via the left facial, trigeminal and greater auricular nerves. The patient presented with left facial droop and paraesthesia. Initial MRI scans demonstrated involvement of the trigeminal and facial nerves with no sign of a primary lesion. Abnormal enhancement within the left parotid substance on FDG PET-CT demonstrated the primary malignancy which was confirmed on histology by core biopsy. There was also focal avidity along the course of the left greater auricular nerve consistent with perineural infiltration, extending from the posterior aspect of the parotid to the left cervical plexus at C2/C3. To our knowledge, this is the second case of squamous cell carcinoma perineural spread to the greater auricular nerve imaged on FDG PET-CT scanning. This case highlights the importance of multimodality imaging correlation in the workup of primary head and neck malignancies and associated perineural spread, which is essential in adjuvant radiation therapy planning to reduce local recurrence, improve prognosis and overall survival.http://www.sciencedirect.com/science/article/pii/S1930043322002552Perineural spreadSquamous cell carcinomaFDG PET-CTMRIGreater auricular nerve |
| spellingShingle | Manvinder Dhillon, BMedSci, MBBS, PGDAAD, MS Gavin Mackie, MBBS, FRANZCR, FAANMS Dalveer Singh, MBBS, FRANZCR, FAANMS 18F-FDG PET, contrast CT and MRI to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerve Radiology Case Reports Perineural spread Squamous cell carcinoma FDG PET-CT MRI Greater auricular nerve |
| title | 18F-FDG PET, contrast CT and MRI to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerve |
| title_full | 18F-FDG PET, contrast CT and MRI to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerve |
| title_fullStr | 18F-FDG PET, contrast CT and MRI to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerve |
| title_full_unstemmed | 18F-FDG PET, contrast CT and MRI to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerve |
| title_short | 18F-FDG PET, contrast CT and MRI to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerve |
| title_sort | 18f fdg pet contrast ct and mri to comprehensively diagnose and assess rare perineural spread of squamous cell carcinoma to the greater auricular nerve |
| topic | Perineural spread Squamous cell carcinoma FDG PET-CT MRI Greater auricular nerve |
| url | http://www.sciencedirect.com/science/article/pii/S1930043322002552 |
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