Cost-impact study of rotavirus vaccination programme in Scotland
Aim: In July 2013, the Scottish Government introduced a rotavirus vaccination programme into the childhood immunisation schedule. The aim of this research was to estimate the cost-impact of this programme. Methods: Data for rotavirus-related resource use were identified including laboratory reports,...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-06-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | http://dx.doi.org/10.1080/21645515.2018.1543522 |
| _version_ | 1797677445577441280 |
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| author | R. Heggie H. Murdoch C. Cameron A. Smith-Palmer E. McIntosh J. Bouttell |
| author_facet | R. Heggie H. Murdoch C. Cameron A. Smith-Palmer E. McIntosh J. Bouttell |
| author_sort | R. Heggie |
| collection | DOAJ |
| description | Aim: In July 2013, the Scottish Government introduced a rotavirus vaccination programme into the childhood immunisation schedule. The aim of this research was to estimate the cost-impact of this programme. Methods: Data for rotavirus-related resource use were identified including laboratory reports, hospitalisations, attendances at accident and emergency departments (A&E), general practice consultations (GP), calls to the National Health Service telephone helpline (NHS24) and prescriptions for common rehydration treatments. We used an interrupted time series analysis approach to assess the impact on resource utilisation in all categories. Appropriate costs were added to the models and predicted pre-and post-vaccination mean annual costs were estimated. The cost of the vaccination programme was estimated using costs from the literature. Results: The vaccination programme was associated with a reduction in utilisation in all measured healthcare resource categories. These reductions were all statistically significant (at the 95% level) with p-values less than 0.001. Reductions ranged from 18% in calls to NHS24 to 73% in positive laboratory reports. The vaccination programme was associated with a reduction in annual healthcare resource costs of 38% (£595,000 per 100,000 infants < 5 years old) in our measured categories (including £495,000 from a reduction in hospital stays). The annual overall cost-impact of the rotavirus vaccination programme (the cost of delivering the programme minus the reduction in resource costs) was estimated at approximately £435,000 per 100,000 infants < 5 years old. Conclusion: The rotavirus vaccination programme was associated with a reduction in all measured categories of rotavirus-related resource use by infants < 5 years old. |
| first_indexed | 2024-03-11T22:45:17Z |
| format | Article |
| id | doaj.art-e403ec1f89344b36a88cd21bb76d8eab |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:45:17Z |
| publishDate | 2019-06-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-e403ec1f89344b36a88cd21bb76d8eab2023-09-22T08:38:24ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2019-06-011561265127110.1080/21645515.2018.15435221543522Cost-impact study of rotavirus vaccination programme in ScotlandR. Heggie0H. Murdoch1C. Cameron2A. Smith-Palmer3E. McIntosh4J. Bouttell5University of GlasgowInstitute of Health and WellbeingInstitute of Health and WellbeingInstitute of Health and WellbeingUniversity of GlasgowUniversity of GlasgowAim: In July 2013, the Scottish Government introduced a rotavirus vaccination programme into the childhood immunisation schedule. The aim of this research was to estimate the cost-impact of this programme. Methods: Data for rotavirus-related resource use were identified including laboratory reports, hospitalisations, attendances at accident and emergency departments (A&E), general practice consultations (GP), calls to the National Health Service telephone helpline (NHS24) and prescriptions for common rehydration treatments. We used an interrupted time series analysis approach to assess the impact on resource utilisation in all categories. Appropriate costs were added to the models and predicted pre-and post-vaccination mean annual costs were estimated. The cost of the vaccination programme was estimated using costs from the literature. Results: The vaccination programme was associated with a reduction in utilisation in all measured healthcare resource categories. These reductions were all statistically significant (at the 95% level) with p-values less than 0.001. Reductions ranged from 18% in calls to NHS24 to 73% in positive laboratory reports. The vaccination programme was associated with a reduction in annual healthcare resource costs of 38% (£595,000 per 100,000 infants < 5 years old) in our measured categories (including £495,000 from a reduction in hospital stays). The annual overall cost-impact of the rotavirus vaccination programme (the cost of delivering the programme minus the reduction in resource costs) was estimated at approximately £435,000 per 100,000 infants < 5 years old. Conclusion: The rotavirus vaccination programme was associated with a reduction in all measured categories of rotavirus-related resource use by infants < 5 years old.http://dx.doi.org/10.1080/21645515.2018.1543522rotaviruscost-impactvaccine |
| spellingShingle | R. Heggie H. Murdoch C. Cameron A. Smith-Palmer E. McIntosh J. Bouttell Cost-impact study of rotavirus vaccination programme in Scotland Human Vaccines & Immunotherapeutics rotavirus cost-impact vaccine |
| title | Cost-impact study of rotavirus vaccination programme in Scotland |
| title_full | Cost-impact study of rotavirus vaccination programme in Scotland |
| title_fullStr | Cost-impact study of rotavirus vaccination programme in Scotland |
| title_full_unstemmed | Cost-impact study of rotavirus vaccination programme in Scotland |
| title_short | Cost-impact study of rotavirus vaccination programme in Scotland |
| title_sort | cost impact study of rotavirus vaccination programme in scotland |
| topic | rotavirus cost-impact vaccine |
| url | http://dx.doi.org/10.1080/21645515.2018.1543522 |
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