Ethical Issues Surrounding Personalized Medicine: A Literature Review

More than a decade ago, personalized medicine was presented in modern medicine. Personalized medicine means that the right drug should be prescribed for the right patient based on genetic data. No doubt is developing medical sciences, and its shift into personalized medicine complicates ethical chal...

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Main Authors: Pooneh Salari, Bagher Larijani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-03-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/6215
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author Pooneh Salari
Bagher Larijani
author_facet Pooneh Salari
Bagher Larijani
author_sort Pooneh Salari
collection DOAJ
description More than a decade ago, personalized medicine was presented in modern medicine. Personalized medicine means that the right drug should be prescribed for the right patient based on genetic data. No doubt is developing medical sciences, and its shift into personalized medicine complicates ethical challenges more than before. In this review, we categorized all probable ethical considerations of personalized medicine in research and development and service provision. Based on our review, extensive changes in healthcare system including ethical changes are needed to overcome the ethical obstacles including knowledge gap and informed consent, privacy and confidentiality and availability of healthcare services. Furthermore social benefit versus science development and individual benefit should be balanced. Therefore guidelines and regulations should be compiled to represent the ethical framework; also ethical decision making should be day-to-day and individualized.
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spelling doaj.art-e40bb7e559fe4210b41eb8494152ec732022-12-21T18:10:03ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942017-03-015535137Ethical Issues Surrounding Personalized Medicine: A Literature ReviewPooneh Salari0Bagher Larijani1Medical Ethics and History of Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical.More than a decade ago, personalized medicine was presented in modern medicine. Personalized medicine means that the right drug should be prescribed for the right patient based on genetic data. No doubt is developing medical sciences, and its shift into personalized medicine complicates ethical challenges more than before. In this review, we categorized all probable ethical considerations of personalized medicine in research and development and service provision. Based on our review, extensive changes in healthcare system including ethical changes are needed to overcome the ethical obstacles including knowledge gap and informed consent, privacy and confidentiality and availability of healthcare services. Furthermore social benefit versus science development and individual benefit should be balanced. Therefore guidelines and regulations should be compiled to represent the ethical framework; also ethical decision making should be day-to-day and individualized.https://acta.tums.ac.ir/index.php/acta/article/view/6215EthicsPersonalized medicinePharmacogenetics studiesGenetic data
spellingShingle Pooneh Salari
Bagher Larijani
Ethical Issues Surrounding Personalized Medicine: A Literature Review
Acta Medica Iranica
Ethics
Personalized medicine
Pharmacogenetics studies
Genetic data
title Ethical Issues Surrounding Personalized Medicine: A Literature Review
title_full Ethical Issues Surrounding Personalized Medicine: A Literature Review
title_fullStr Ethical Issues Surrounding Personalized Medicine: A Literature Review
title_full_unstemmed Ethical Issues Surrounding Personalized Medicine: A Literature Review
title_short Ethical Issues Surrounding Personalized Medicine: A Literature Review
title_sort ethical issues surrounding personalized medicine a literature review
topic Ethics
Personalized medicine
Pharmacogenetics studies
Genetic data
url https://acta.tums.ac.ir/index.php/acta/article/view/6215
work_keys_str_mv AT poonehsalari ethicalissuessurroundingpersonalizedmedicinealiteraturereview
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