Effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patients
Abstract Background To observe the effects of conventional theatre nursing combined with transcutaneous electrical acupoint stimulation (TEAS) on postoperative cognitive dysfunction (POCD) in elderly total knee arthroplasty (TKA) patients. Methods Forty elderly TKA patients were randomly divided int...
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| Format: | Article |
| Language: | English |
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BMC
2024-02-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | https://doi.org/10.1186/s13018-023-04348-6 |
| _version_ | 1797273843920797696 |
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| author | Xinxin Wang Jia Zhou Gaojiao Zhang |
| author_facet | Xinxin Wang Jia Zhou Gaojiao Zhang |
| author_sort | Xinxin Wang |
| collection | DOAJ |
| description | Abstract Background To observe the effects of conventional theatre nursing combined with transcutaneous electrical acupoint stimulation (TEAS) on postoperative cognitive dysfunction (POCD) in elderly total knee arthroplasty (TKA) patients. Methods Forty elderly TKA patients were randomly divided into a conventional nursing (control) group and a TEAS group. Using conventional nursing, TEAS was used to stimulate the “Zusanli” and “Sanyinjiao” in the healthy leg of patients in the TEAS group. All patients received mini-mental (MMSE) scores 1 day before surgery (T0) and 1, 3, and 7 days after surgery (T1, T3, T7). Plasma levels of interleukin-1 (IL-1β), interleukin-6 (IL-6), tumor necrosis factor (TNF-α), and S100β were measured using venous blood samples. Results There were no significant differences in baseline clinical characteristics between the two groups. Compared to T0, the MMSE scores of patients in the control group were significantly reduced at T1 and T3 (P < 0.05). Compared to the control group, the MMSE scores of patients in the TEAS group increased significantly at T3 (P < 0.05). The incidence of POCD in the TEAS group was 10%, lower than in the control group (40%) (P < 0.05). The levels of IL-1β, IL-6, TNF-α and S-100β in patients in the TEAS group were lower than in the control group on days T1, T3 and T7 (P < 0.05). Conclusion Conventional intraoperative nursing combined with TEAS can reduce the incidence of POCD. The possible mechanism is related to the reduction of inflammatory response and neuronal injury with TEAS. Clinical registration number: ChiCTR2300070281. |
| first_indexed | 2024-03-07T14:50:01Z |
| format | Article |
| id | doaj.art-e40dbbb0ef8f4b73b67283de974a3cad |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-03-07T14:50:01Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-e40dbbb0ef8f4b73b67283de974a3cad2024-03-05T19:45:31ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2024-02-011811710.1186/s13018-023-04348-6Effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patientsXinxin Wang0Jia Zhou1Gaojiao Zhang2Department of Operation Room, Wenzhou Hospital of Integrated Traditional Chinese and Western MedicineDepartment of Operation Room, Wenzhou Hospital of Integrated Traditional Chinese and Western MedicineDepartment of Anesthesiology, Wenzhou Hospital of Integrated Traditional Chinese and Western MedicineAbstract Background To observe the effects of conventional theatre nursing combined with transcutaneous electrical acupoint stimulation (TEAS) on postoperative cognitive dysfunction (POCD) in elderly total knee arthroplasty (TKA) patients. Methods Forty elderly TKA patients were randomly divided into a conventional nursing (control) group and a TEAS group. Using conventional nursing, TEAS was used to stimulate the “Zusanli” and “Sanyinjiao” in the healthy leg of patients in the TEAS group. All patients received mini-mental (MMSE) scores 1 day before surgery (T0) and 1, 3, and 7 days after surgery (T1, T3, T7). Plasma levels of interleukin-1 (IL-1β), interleukin-6 (IL-6), tumor necrosis factor (TNF-α), and S100β were measured using venous blood samples. Results There were no significant differences in baseline clinical characteristics between the two groups. Compared to T0, the MMSE scores of patients in the control group were significantly reduced at T1 and T3 (P < 0.05). Compared to the control group, the MMSE scores of patients in the TEAS group increased significantly at T3 (P < 0.05). The incidence of POCD in the TEAS group was 10%, lower than in the control group (40%) (P < 0.05). The levels of IL-1β, IL-6, TNF-α and S-100β in patients in the TEAS group were lower than in the control group on days T1, T3 and T7 (P < 0.05). Conclusion Conventional intraoperative nursing combined with TEAS can reduce the incidence of POCD. The possible mechanism is related to the reduction of inflammatory response and neuronal injury with TEAS. Clinical registration number: ChiCTR2300070281.https://doi.org/10.1186/s13018-023-04348-6Conventional nursing in operating roomInflammatory factorsPostoperative cognitive dysfunctionS100β proteinTranscutaneous electrical acupoint stimulation |
| spellingShingle | Xinxin Wang Jia Zhou Gaojiao Zhang Effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patients Journal of Orthopaedic Surgery and Research Conventional nursing in operating room Inflammatory factors Postoperative cognitive dysfunction S100β protein Transcutaneous electrical acupoint stimulation |
| title | Effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patients |
| title_full | Effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patients |
| title_fullStr | Effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patients |
| title_full_unstemmed | Effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patients |
| title_short | Effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patients |
| title_sort | effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patients |
| topic | Conventional nursing in operating room Inflammatory factors Postoperative cognitive dysfunction S100β protein Transcutaneous electrical acupoint stimulation |
| url | https://doi.org/10.1186/s13018-023-04348-6 |
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