Rheumatological Manifestations Associated with Viral Hepatitis B or C
Abstract INTRODUCTION Rheumatological findings and rheumatic diseases may be associated with hepatitis virus infection. This study assessed the frequency of these manifestations in a reference unit in Acre, Brazil. METHODS This was a cross-sectional study with a convenience sample of patients ha...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2019-12-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100343&tlng=en |
| _version_ | 1811245523452035072 |
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| author | Ídila Mont’Alverne Xavier de Oliveira Rita do Socorro Uchôa da Silva |
| author_facet | Ídila Mont’Alverne Xavier de Oliveira Rita do Socorro Uchôa da Silva |
| author_sort | Ídila Mont’Alverne Xavier de Oliveira |
| collection | DOAJ |
| description | Abstract INTRODUCTION Rheumatological findings and rheumatic diseases may be associated with hepatitis virus infection. This study assessed the frequency of these manifestations in a reference unit in Acre, Brazil. METHODS This was a cross-sectional study with a convenience sample of patients having their first consultation at the rheumatology outpatient clinics of a referral unit in Rio Branco, Acre, from March to November 2017. Sociodemographic, clinical, laboratory, and imaging data registereds using a standardized questionnaire form. RESULTS Among the 600 patients with rheumatic complaints, 3.0% were newly diagnosed with hepatitis B virus (HBV) or hepatitis C virus (HCV), and 8.7% were previously diagnosed with hepatitis. Among the 70 patients with hepatitis, 54.3% were carriers of HBV and 45.7% of HCV. For patients infected with HBV and HCV, arthralgia was the most prevalent rheumatic manifestation in 97.4% and 90.6%, followed by myalgia in 81.6% and 65.6%, and arthritis in 26.3% and 40.6% of patients, respectively, according to the descriptive analysis performed using the Statistical Package for the Social Sciences software. In comparative analyses using the chi-squared test, despite the fact that fibromyalgia was the most prevalent rheumatic disease only the Rheumatoid Arthritis there were differences in distribution between the carriers of HCV (18.8%) and HBV (2.6%). According to the Fisher’s exact test, hypothyroidism was the most frequent comorbidity in patients with HCV (21.9%). CONCLUSIONS An increased frequency of musculoskeletal manifestations, better than those reported in the medical literature, in patients infected with HBV and HCV was observed. |
| first_indexed | 2024-04-12T14:41:07Z |
| format | Article |
| id | doaj.art-e40fee47b0f843eca80f49b4a1d5d477 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T14:41:07Z |
| publishDate | 2019-12-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-e40fee47b0f843eca80f49b4a1d5d4772022-12-22T03:28:51ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492019-12-015210.1590/0037-8682-0407-2018Rheumatological Manifestations Associated with Viral Hepatitis B or CÍdila Mont’Alverne Xavier de OliveiraRita do Socorro Uchôa da Silvahttps://orcid.org/0000-0003-0481-0732Abstract INTRODUCTION Rheumatological findings and rheumatic diseases may be associated with hepatitis virus infection. This study assessed the frequency of these manifestations in a reference unit in Acre, Brazil. METHODS This was a cross-sectional study with a convenience sample of patients having their first consultation at the rheumatology outpatient clinics of a referral unit in Rio Branco, Acre, from March to November 2017. Sociodemographic, clinical, laboratory, and imaging data registereds using a standardized questionnaire form. RESULTS Among the 600 patients with rheumatic complaints, 3.0% were newly diagnosed with hepatitis B virus (HBV) or hepatitis C virus (HCV), and 8.7% were previously diagnosed with hepatitis. Among the 70 patients with hepatitis, 54.3% were carriers of HBV and 45.7% of HCV. For patients infected with HBV and HCV, arthralgia was the most prevalent rheumatic manifestation in 97.4% and 90.6%, followed by myalgia in 81.6% and 65.6%, and arthritis in 26.3% and 40.6% of patients, respectively, according to the descriptive analysis performed using the Statistical Package for the Social Sciences software. In comparative analyses using the chi-squared test, despite the fact that fibromyalgia was the most prevalent rheumatic disease only the Rheumatoid Arthritis there were differences in distribution between the carriers of HCV (18.8%) and HBV (2.6%). According to the Fisher’s exact test, hypothyroidism was the most frequent comorbidity in patients with HCV (21.9%). CONCLUSIONS An increased frequency of musculoskeletal manifestations, better than those reported in the medical literature, in patients infected with HBV and HCV was observed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100343&tlng=enViral hepatitisArthralgiaRheumatic diseasesRheumatoid arthritisWestern Amazon |
| spellingShingle | Ídila Mont’Alverne Xavier de Oliveira Rita do Socorro Uchôa da Silva Rheumatological Manifestations Associated with Viral Hepatitis B or C Revista da Sociedade Brasileira de Medicina Tropical Viral hepatitis Arthralgia Rheumatic diseases Rheumatoid arthritis Western Amazon |
| title | Rheumatological Manifestations Associated with Viral Hepatitis B or C |
| title_full | Rheumatological Manifestations Associated with Viral Hepatitis B or C |
| title_fullStr | Rheumatological Manifestations Associated with Viral Hepatitis B or C |
| title_full_unstemmed | Rheumatological Manifestations Associated with Viral Hepatitis B or C |
| title_short | Rheumatological Manifestations Associated with Viral Hepatitis B or C |
| title_sort | rheumatological manifestations associated with viral hepatitis b or c |
| topic | Viral hepatitis Arthralgia Rheumatic diseases Rheumatoid arthritis Western Amazon |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100343&tlng=en |
| work_keys_str_mv | AT idilamontalvernexavierdeoliveira rheumatologicalmanifestationsassociatedwithviralhepatitisborc AT ritadosocorrouchoadasilva rheumatologicalmanifestationsassociatedwithviralhepatitisborc |