Effect of semaglutide and empagliflozin on cognitive function and hippocampal phosphoproteomic in obese mice

Effect of semaglutide and empagliflozin on cognitive function and hippocampal phosphoproteomic in obese mice

Objective: Based on the 4D label-free phosphoproteomic technique, we examined the differences in cognitive function and hippocampal phosphorylated protein expression in high-fat diet-induced obese mice after the intervention of semaglutide and empagliflozin, as well as the effects of both on protein...

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Bibliographic Details
Main Authors: Xiaoyi Chen, Shuchun Chen, Zelin Li, Ruiyi Zhu, Zhuoya Jia, Jiangli Ban, Ruoxi Zhen, Xing Chen, Xiaoyu Pan, Qingjuan Ren, Lin Yue, Shu Niu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
semaglutide
empagliflozin
phosphoproteomic
obesity
cognitive impairment
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.975830/full

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