Signaling levels mold the RAS mutation tropism of urethane
RAS genes are commonly mutated in human cancer. Despite many possible mutations, individual cancer types often have a ‘tropism’ towards a specific subset of RAS mutations. As driver mutations, these patterns ostensibly originate from normal cells. High oncogenic RAS activity causes oncogenic stress...
| Hlavní autoři: | , |
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| Médium: | Článek |
| Jazyk: | English |
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eLife Sciences Publications Ltd
2021-05-01
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| Edice: | eLife |
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| On-line přístup: | https://elifesciences.org/articles/67172 |