Bioassays for TSH receptor autoantibodies, from FRTL-5 cells to TSH receptor–LH/CG receptor chimeras: the contribution of Leonard D. Kohn

Bioassays for TSH receptor autoantibodies, from FRTL-5 cells to TSH receptor–LH/CG receptor chimeras: the contribution of Leonard D. Kohn

Since the discovery 60 years ago of the long-acting thyroid stimulator by Adams and Purves, great progress has been made in the detection of thyroid-stimulating hormone (TSH) receptor autoantibodies (TRAbs) in Graves’ disease. Today, commercial assays are available that can detect TRAbs with high ac...

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Bibliographic Details
Main Authors: Cesidio Giuliani, Motoyasu Saji, Ines Bucci, Giorgio Napolitano
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Endocrinology
Subjects:
Chimera
Graves’ disease
FRTL-5 cells
TSH receptor bioassay
TSHR autoantibodies
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00103/full

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