Adeno-Associated Virus (AAV) Gene Delivery: Dissecting Molecular Interactions upon Cell Entry

Adeno-Associated Virus (AAV) Gene Delivery: Dissecting Molecular Interactions upon Cell Entry

Human gene therapy has advanced from twentieth-century conception to twenty-first-century reality. The recombinant Adeno-Associated Virus (rAAV) is a major gene therapy vector. Research continues to improve rAAV safety and efficacy using a variety of AAV capsid modification strategies. Significant f...

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Bibliographic Details
Main Authors: Edward E. Large, Mark A. Silveria, Grant M. Zane, Onellah Weerakoon, Michael S. Chapman
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
adeno-associated virus
AAV
gene therapy
virus structure
AAV receptor
AAV attachment factor
Online Access:https://www.mdpi.com/1999-4915/13/7/1336

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