The potential health benefits of haskap (Lonicera caerulea L.): Role of cyanidin-3-O-glucoside
Haskap (Lonicera caerulea L.), an emerging commercial fruit crop in North America, has been known for its medicinal benefits amongst the people of Russia, Japan, and Northeastern China for centuries. The vitamin C content in haskap berries, ranging between 29 and 187 mg/100 g, is significantly highe...
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| Format: | Article |
| Language: | English |
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Elsevier
2018-05-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464618300689 |
| _version_ | 1818953777054482432 |
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| author | H.P. Vasantha Rupasinghe Niroshaathevi Arumuggam Madumani Amararathna A.B.K.H. De Silva |
| author_facet | H.P. Vasantha Rupasinghe Niroshaathevi Arumuggam Madumani Amararathna A.B.K.H. De Silva |
| author_sort | H.P. Vasantha Rupasinghe |
| collection | DOAJ |
| description | Haskap (Lonicera caerulea L.), an emerging commercial fruit crop in North America, has been known for its medicinal benefits amongst the people of Russia, Japan, and Northeastern China for centuries. The vitamin C content in haskap berries, ranging between 29 and 187 mg/100 g, is significantly higher than in other vitamin C-rich sources such as oranges, strawberries, and raspberries. Cyanidin-3-O-glucoside (C3G) is the major anthocyanin present in haskap comprising about 79–92% of its total anthocyanin content and over 60% of the total polyphenols. Considerable evidence shows significant antioxidant, cardio-protective, anti-inflammatory, neuroprotective, anticancer, and anti-diabetic properties of C3G-rich haskap preparations and C3G alone both in vitro and in vivo. This review broadly discusses the in vitro and pre-clinical significance of haskap-mediated cytoprotection and disease prevention; thereby, we strongly suggest further exploration of C3G-rich haskap preparations as potential functional food, dietary antioxidant supplements as well as natural health products targeting specific chronic and metabolic diseases. |
| first_indexed | 2024-12-20T10:11:39Z |
| format | Article |
| id | doaj.art-e4250a7b627b430ab7b8f942318b58b7 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-20T10:11:39Z |
| publishDate | 2018-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-e4250a7b627b430ab7b8f942318b58b72022-12-21T19:44:08ZengElsevierJournal of Functional Foods1756-46462018-05-01442439The potential health benefits of haskap (Lonicera caerulea L.): Role of cyanidin-3-O-glucosideH.P. Vasantha Rupasinghe0Niroshaathevi Arumuggam1Madumani Amararathna2A.B.K.H. De Silva3Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia, Canada; Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada; Corresponding author at: Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia, Canada.Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia, CanadaDepartment of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia, Canada; Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, CanadaDepartment of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia, CanadaHaskap (Lonicera caerulea L.), an emerging commercial fruit crop in North America, has been known for its medicinal benefits amongst the people of Russia, Japan, and Northeastern China for centuries. The vitamin C content in haskap berries, ranging between 29 and 187 mg/100 g, is significantly higher than in other vitamin C-rich sources such as oranges, strawberries, and raspberries. Cyanidin-3-O-glucoside (C3G) is the major anthocyanin present in haskap comprising about 79–92% of its total anthocyanin content and over 60% of the total polyphenols. Considerable evidence shows significant antioxidant, cardio-protective, anti-inflammatory, neuroprotective, anticancer, and anti-diabetic properties of C3G-rich haskap preparations and C3G alone both in vitro and in vivo. This review broadly discusses the in vitro and pre-clinical significance of haskap-mediated cytoprotection and disease prevention; thereby, we strongly suggest further exploration of C3G-rich haskap preparations as potential functional food, dietary antioxidant supplements as well as natural health products targeting specific chronic and metabolic diseases.http://www.sciencedirect.com/science/article/pii/S1756464618300689AntioxidantsAnthocyaninPolyphenolsOxidative stressChronic diseasesPhysiological function |
| spellingShingle | H.P. Vasantha Rupasinghe Niroshaathevi Arumuggam Madumani Amararathna A.B.K.H. De Silva The potential health benefits of haskap (Lonicera caerulea L.): Role of cyanidin-3-O-glucoside Journal of Functional Foods Antioxidants Anthocyanin Polyphenols Oxidative stress Chronic diseases Physiological function |
| title | The potential health benefits of haskap (Lonicera caerulea L.): Role of cyanidin-3-O-glucoside |
| title_full | The potential health benefits of haskap (Lonicera caerulea L.): Role of cyanidin-3-O-glucoside |
| title_fullStr | The potential health benefits of haskap (Lonicera caerulea L.): Role of cyanidin-3-O-glucoside |
| title_full_unstemmed | The potential health benefits of haskap (Lonicera caerulea L.): Role of cyanidin-3-O-glucoside |
| title_short | The potential health benefits of haskap (Lonicera caerulea L.): Role of cyanidin-3-O-glucoside |
| title_sort | potential health benefits of haskap lonicera caerulea l role of cyanidin 3 o glucoside |
| topic | Antioxidants Anthocyanin Polyphenols Oxidative stress Chronic diseases Physiological function |
| url | http://www.sciencedirect.com/science/article/pii/S1756464618300689 |
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