Effects of BRCA1 Transgene Expression on Murine Mammary Gland Development and Mutagen-Induced Mammary Neoplasia

Effects of BRCA1 Transgene Expression on Murine Mammary Gland Development and Mutagen-Induced Mammary Neoplasia

<p>To characterize the role of <i>BRCA1</i> in mammary gland development and tumor suppression, a transgenic mouse model of <i>BRCA1</i> overexpression was developed. Using the mouse mammary tumor virus (MMTV) promoter/enhancer, transgenic mice expressing human BRCA1 or...

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Bibliographic Details
Main Author:	Arichika Hoshino, Cindy J. Yee, Mel Campbell, Randall L. Woltjer, Rebecca L. Townsend, Riet van der Meer, Yu Shyr, Jeffrey T. Holt, Harold L. Moses, Roy A. Jensen
Format:	Article
Language:	English
Published:	Ivyspring International Publisher 2007-01-01
Series:	International Journal of Biological Sciences
Online Access:	http://www.biolsci.org/v03p0281.htm

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