Improving Medication‐Related Outcomes in Chronic Liver Disease

Patients with chronic liver disease (CLD) are becoming increasingly complex due to the rising prevalence of multimorbidity and polypharmacy. Medications are often essential to manage the underlying liver disease, complications of cirrhosis and portal hypertension, and comorbidities. However, medicat...

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Main Authors: Kelly L. Hayward, Rianne A. Weersink
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2020-11-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1612
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author Kelly L. Hayward
Rianne A. Weersink
author_facet Kelly L. Hayward
Rianne A. Weersink
author_sort Kelly L. Hayward
collection DOAJ
description Patients with chronic liver disease (CLD) are becoming increasingly complex due to the rising prevalence of multimorbidity and polypharmacy. Medications are often essential to manage the underlying liver disease, complications of cirrhosis and portal hypertension, and comorbidities. However, medication‐related problems (MRPs) have been associated with adverse patient outcomes, including hospitalization and mortality. Factors that can contribute to MRPs in people with CLD are variable and often entwined. This narrative literature review discusses key barriers and opportunities to modify risk factors and improve medication‐related outcomes for people with CLD.
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spelling doaj.art-e4269a9e935d401eac40baf5f19196012023-09-03T02:44:27ZengWolters Kluwer Health/LWWHepatology Communications2471-254X2020-11-014111562157710.1002/hep4.1612Improving Medication‐Related Outcomes in Chronic Liver DiseaseKelly L. Hayward0Rianne A. Weersink1Centre for Liver Disease Research, Faculty of Medicine The University of Queensland, Translational Research Institute Brisbane QLD AustraliaDepartment of Clinical Pharmacy Deventer Hospital Deventer The NetherlandsPatients with chronic liver disease (CLD) are becoming increasingly complex due to the rising prevalence of multimorbidity and polypharmacy. Medications are often essential to manage the underlying liver disease, complications of cirrhosis and portal hypertension, and comorbidities. However, medication‐related problems (MRPs) have been associated with adverse patient outcomes, including hospitalization and mortality. Factors that can contribute to MRPs in people with CLD are variable and often entwined. This narrative literature review discusses key barriers and opportunities to modify risk factors and improve medication‐related outcomes for people with CLD.https://doi.org/10.1002/hep4.1612
spellingShingle Kelly L. Hayward
Rianne A. Weersink
Improving Medication‐Related Outcomes in Chronic Liver Disease
Hepatology Communications
title Improving Medication‐Related Outcomes in Chronic Liver Disease
title_full Improving Medication‐Related Outcomes in Chronic Liver Disease
title_fullStr Improving Medication‐Related Outcomes in Chronic Liver Disease
title_full_unstemmed Improving Medication‐Related Outcomes in Chronic Liver Disease
title_short Improving Medication‐Related Outcomes in Chronic Liver Disease
title_sort improving medication related outcomes in chronic liver disease
url https://doi.org/10.1002/hep4.1612
work_keys_str_mv AT kellylhayward improvingmedicationrelatedoutcomesinchronicliverdisease
AT rianneaweersink improvingmedicationrelatedoutcomesinchronicliverdisease