Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
What happens to cells on engrafting into the brain in animal models to treat Parkinson’s disease is unclear. Here, the authors use scRNA-seq to examine ventral midbrain (VM)-patterned human embryonic stem cells after functional maturation in a pre-clinical rat model for Parkinson’s disease and ident...
Full description
Bibliographic Details
| Main Authors: |
Katarína Tiklová,
Sara Nolbrant,
Alessandro Fiorenzano,
Åsa K. Björklund,
Yogita Sharma,
Andreas Heuer,
Linda Gillberg,
Deirdre B. Hoban,
Tiago Cardoso,
Andrew F. Adler,
Marcella Birtele,
Hilda Lundén-Miguel,
Nikolaos Volakakis,
Agnete Kirkeby,
Thomas Perlmann,
Malin Parmar |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Portfolio
2020-05-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-020-16225-5
|
|---|