Study of marine microorganism metabolites: new resources for bioactive natural products
The marine environment has remained a source of novel biological molecules with diversified applications. The ecological and biological diversity, along with a unique physical environment, have provided the evolutionary advantage to the plant, animals and microbial species thriving in the marine eco...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1285902/full |
| _version_ | 1827387689505128448 |
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| author | Noora Barzkar Stanislav Sukhikh Olga Babich |
| author_facet | Noora Barzkar Stanislav Sukhikh Olga Babich |
| author_sort | Noora Barzkar |
| collection | DOAJ |
| description | The marine environment has remained a source of novel biological molecules with diversified applications. The ecological and biological diversity, along with a unique physical environment, have provided the evolutionary advantage to the plant, animals and microbial species thriving in the marine ecosystem. In light of the fact that marine microorganisms frequently interact symbiotically or mutualistically with higher species including corals, fish, sponges, and algae, this paper intends to examine the potential of marine microorganisms as a niche for marine bacteria. This review aims to analyze and summarize modern literature data on the biotechnological potential of marine fungi and bacteria as producers of a wide range of practically valuable products (surfactants, glyco-and lipopeptides, exopolysaccharides, enzymes, and metabolites with different biological activities: antimicrobial, antitumor, and cytotoxic). Hence, the study on bioactive secondary metabolites from marine microorganisms is the need of the hour. The scientific novelty of the study lies in the fact that for the first time, the data on new resources for obtaining biologically active natural products — metabolites of marine bacteria and fungi — were generalized. The review investigates the various kinds of natural products derived from marine microorganisms, specifically focusing on marine bacteria and fungi as a valuable source for new natural products. It provides a summary of the data regarding the antibacterial, antimalarial, anticarcinogenic, antibiofilm, and anti-inflammatory effects demonstrated by marine microorganisms. There is currently a great need for scientific and applied research on bioactive secondary metabolites of marine microorganisms from the standpoint of human and animal health. |
| first_indexed | 2024-03-08T16:06:52Z |
| format | Article |
| id | doaj.art-e42a622c856f4e89b3cc9bbaae0e8623 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-03-08T16:06:52Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-e42a622c856f4e89b3cc9bbaae0e86232024-01-08T05:45:42ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2024-01-011410.3389/fmicb.2023.12859021285902Study of marine microorganism metabolites: new resources for bioactive natural productsNoora Barzkar0Stanislav Sukhikh1Olga Babich2Department of Agro-Industrial Technology, Faculty of Applied Science, Food and Agro-Industrial Research Center, King Mongkut’s University of Technology North Bangkok, Bangkok, ThailandResearch and Education Center “Industrial Biotechnologies”, Immanuel Kant Baltic Federal University, Kaliningrad, RussiaResearch and Education Center “Industrial Biotechnologies”, Immanuel Kant Baltic Federal University, Kaliningrad, RussiaThe marine environment has remained a source of novel biological molecules with diversified applications. The ecological and biological diversity, along with a unique physical environment, have provided the evolutionary advantage to the plant, animals and microbial species thriving in the marine ecosystem. In light of the fact that marine microorganisms frequently interact symbiotically or mutualistically with higher species including corals, fish, sponges, and algae, this paper intends to examine the potential of marine microorganisms as a niche for marine bacteria. This review aims to analyze and summarize modern literature data on the biotechnological potential of marine fungi and bacteria as producers of a wide range of practically valuable products (surfactants, glyco-and lipopeptides, exopolysaccharides, enzymes, and metabolites with different biological activities: antimicrobial, antitumor, and cytotoxic). Hence, the study on bioactive secondary metabolites from marine microorganisms is the need of the hour. The scientific novelty of the study lies in the fact that for the first time, the data on new resources for obtaining biologically active natural products — metabolites of marine bacteria and fungi — were generalized. The review investigates the various kinds of natural products derived from marine microorganisms, specifically focusing on marine bacteria and fungi as a valuable source for new natural products. It provides a summary of the data regarding the antibacterial, antimalarial, anticarcinogenic, antibiofilm, and anti-inflammatory effects demonstrated by marine microorganisms. There is currently a great need for scientific and applied research on bioactive secondary metabolites of marine microorganisms from the standpoint of human and animal health.https://www.frontiersin.org/articles/10.3389/fmicb.2023.1285902/fullmarine bacteria and fungimetabolites for disease prevention and treatmentbiological activitybioactive compoundshuman health |
| spellingShingle | Noora Barzkar Stanislav Sukhikh Olga Babich Study of marine microorganism metabolites: new resources for bioactive natural products Frontiers in Microbiology marine bacteria and fungi metabolites for disease prevention and treatment biological activity bioactive compounds human health |
| title | Study of marine microorganism metabolites: new resources for bioactive natural products |
| title_full | Study of marine microorganism metabolites: new resources for bioactive natural products |
| title_fullStr | Study of marine microorganism metabolites: new resources for bioactive natural products |
| title_full_unstemmed | Study of marine microorganism metabolites: new resources for bioactive natural products |
| title_short | Study of marine microorganism metabolites: new resources for bioactive natural products |
| title_sort | study of marine microorganism metabolites new resources for bioactive natural products |
| topic | marine bacteria and fungi metabolites for disease prevention and treatment biological activity bioactive compounds human health |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1285902/full |
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