Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T<sub>1</sub> and T<sub>2</sub> Relaxation Times with Application to Cancer Cell Culture

Artificial intelligence has been entering medical research. Today, manufacturers of diagnostic instruments are including algorithms based on neural networks. Neural networks are quickly entering all branches of medical research and beyond. Analyzing the PubMed database from the last 5 years (2017 to...

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Main Authors: Adrian Truszkiewicz, Dorota Bartusik-Aebisher, Łukasz Wojtas, Grzegorz Cieślar, Aleksandra Kawczyk-Krupka, David Aebisher
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/2/1554
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author Adrian Truszkiewicz
Dorota Bartusik-Aebisher
Łukasz Wojtas
Grzegorz Cieślar
Aleksandra Kawczyk-Krupka
David Aebisher
author_facet Adrian Truszkiewicz
Dorota Bartusik-Aebisher
Łukasz Wojtas
Grzegorz Cieślar
Aleksandra Kawczyk-Krupka
David Aebisher
author_sort Adrian Truszkiewicz
collection DOAJ
description Artificial intelligence has been entering medical research. Today, manufacturers of diagnostic instruments are including algorithms based on neural networks. Neural networks are quickly entering all branches of medical research and beyond. Analyzing the PubMed database from the last 5 years (2017 to 2021), we see that the number of responses to the query “neural network in medicine” exceeds 10,500 papers. Deep learning algorithms are of particular importance in oncology. This paper presents the use of neural networks to analyze the magnetic resonance imaging (MRI) images used to determine MRI relaxometry of the samples. Relaxometry is becoming an increasingly common tool in diagnostics. The aim of this work was to optimize the processing time of DICOM images by using a neural network implemented in the MATLAB package by The MathWorks with the patternnet function. The application of a neural network helps to eliminate spaces in which there are no objects with characteristics matching the phenomenon of longitudinal or transverse MRI relaxation. The result of this work is the elimination of aerated spaces in MRI images. The whole algorithm was implemented as an application in the MATLAB package.
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spelling doaj.art-e42a959a25fc4e02ae088fe8b26694a92023-11-30T22:42:12ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-01-01242155410.3390/ijms24021554Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T<sub>1</sub> and T<sub>2</sub> Relaxation Times with Application to Cancer Cell CultureAdrian Truszkiewicz0Dorota Bartusik-Aebisher1Łukasz Wojtas2Grzegorz Cieślar3Aleksandra Kawczyk-Krupka4David Aebisher5Department of Photomedicine and Physical Chemistry, Medical College of University of Rzeszów, University of Rzeszów, Warzywna 1A Street, 35-310 Rzeszów, PolandDepartment of Biochemistry and General Chemistry, Medical College of University of Rzeszów, University of Rzeszów, Kopisto 2a Street, 35-959 Rzeszów, PolandDepartment of Medical Equipment, Provincial Clinical Hospital No. 2, 35-959 Rzeszów, PolandDepartment of Internal Medicine, Angiology and Physical Medicine, Center for Laser Diagnostics and Therapy, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Internal Medicine, Angiology and Physical Medicine, Center for Laser Diagnostics and Therapy, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Photomedicine and Physical Chemistry, Medical College of University of Rzeszów, University of Rzeszów, Warzywna 1A Street, 35-310 Rzeszów, PolandArtificial intelligence has been entering medical research. Today, manufacturers of diagnostic instruments are including algorithms based on neural networks. Neural networks are quickly entering all branches of medical research and beyond. Analyzing the PubMed database from the last 5 years (2017 to 2021), we see that the number of responses to the query “neural network in medicine” exceeds 10,500 papers. Deep learning algorithms are of particular importance in oncology. This paper presents the use of neural networks to analyze the magnetic resonance imaging (MRI) images used to determine MRI relaxometry of the samples. Relaxometry is becoming an increasingly common tool in diagnostics. The aim of this work was to optimize the processing time of DICOM images by using a neural network implemented in the MATLAB package by The MathWorks with the patternnet function. The application of a neural network helps to eliminate spaces in which there are no objects with characteristics matching the phenomenon of longitudinal or transverse MRI relaxation. The result of this work is the elimination of aerated spaces in MRI images. The whole algorithm was implemented as an application in the MATLAB package.https://www.mdpi.com/1422-0067/24/2/1554MATLABT1T2relaxation timesMR
spellingShingle Adrian Truszkiewicz
Dorota Bartusik-Aebisher
Łukasz Wojtas
Grzegorz Cieślar
Aleksandra Kawczyk-Krupka
David Aebisher
Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T<sub>1</sub> and T<sub>2</sub> Relaxation Times with Application to Cancer Cell Culture
International Journal of Molecular Sciences
MATLAB
T1
T2
relaxation times
MR
title Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T<sub>1</sub> and T<sub>2</sub> Relaxation Times with Application to Cancer Cell Culture
title_full Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T<sub>1</sub> and T<sub>2</sub> Relaxation Times with Application to Cancer Cell Culture
title_fullStr Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T<sub>1</sub> and T<sub>2</sub> Relaxation Times with Application to Cancer Cell Culture
title_full_unstemmed Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T<sub>1</sub> and T<sub>2</sub> Relaxation Times with Application to Cancer Cell Culture
title_short Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T<sub>1</sub> and T<sub>2</sub> Relaxation Times with Application to Cancer Cell Culture
title_sort neural network in the analysis of the mr signal as an image segmentation tool for the determination of t sub 1 sub and t sub 2 sub relaxation times with application to cancer cell culture
topic MATLAB
T1
T2
relaxation times
MR
url https://www.mdpi.com/1422-0067/24/2/1554
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