A multidrug ABC transporter with a taste for salt.

A multidrug ABC transporter with a taste for salt.

BACKGROUND:LmrA is a multidrug ATP-binding cassette (ABC) transporter from Lactococcus lactis with no known physiological substrate, which can transport a wide range of chemotherapeutic agents and toxins from the cell. The protein can functionally replace the human homologue ABCB1 (also termed multi...

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Main Authors: Saroj Velamakanni, Calvin H F Lau, Daniel A P Gutmann, Henrietta Venter, Nelson P Barrera, Markus A Seeger, Barbara Woebking, Dijana Matak-Vinkovic, Lekshmy Balakrishnan, Yao Yao, Edmond C Y U, Richard A Shilling, Carol V Robinson, Peter Thorn, Hendrik W van Veen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2704374?pdf=render

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