Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient

Cryptococcus neoformans is generally observed with immunosuppressive conditions. Rarely, it may be seen in immunocompetent individuals and presented with non-specific conditions. We described an immunocompetent case of cryptococcal meningitis presented with multiple cerebral infarcts. Despite the la...

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Main Authors: Buket Erturk Sengel, Elif Tukenmez Tigen, Rabia Can Sarinoglu, Ipek Midi, Nilgun Cerikcioglu, Zekaver Odabasi
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:IDCases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250921001104
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author Buket Erturk Sengel
Elif Tukenmez Tigen
Rabia Can Sarinoglu
Ipek Midi
Nilgun Cerikcioglu
Zekaver Odabasi
author_facet Buket Erturk Sengel
Elif Tukenmez Tigen
Rabia Can Sarinoglu
Ipek Midi
Nilgun Cerikcioglu
Zekaver Odabasi
author_sort Buket Erturk Sengel
collection DOAJ
description Cryptococcus neoformans is generally observed with immunosuppressive conditions. Rarely, it may be seen in immunocompetent individuals and presented with non-specific conditions. We described an immunocompetent case of cryptococcal meningitis presented with multiple cerebral infarcts. Despite the late diagnosis and emergence of hydrocephalus during treatment, the patient was recovered without any sequelae. In immunocompetent patients, the conventional diagnostics tests may be negative because of the low fungal load. If it is available, the Biofire FilmArray meningitis panel has high sensitivity and specificity for diagnosis.
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spelling doaj.art-e42e225d6a6644b482765f25f1b4d3632022-12-21T18:58:37ZengElsevierIDCases2214-25092021-01-0124e01154Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patientBuket Erturk Sengel0Elif Tukenmez Tigen1Rabia Can Sarinoglu2Ipek Midi3Nilgun Cerikcioglu4Zekaver Odabasi5Marmara University, Faculty of Medicine, Infectious Disease and Clinical Microbiology, Istanbul, Turkey; Corresponding author at: Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi, Fevzi Çakmak Mah. Muhsin Yazıcıoğlu Cad. No:10, Pendik, İstanbul, Turkey.Marmara University, Faculty of Medicine, Infectious Disease and Clinical Microbiology, Istanbul, TurkeyMarmara University, Faculty of Medicine, Medical Microbiology, Istanbul, TurkeyMarmara University, Faculty of Medicine, Neurology, Istanbul, TurkeyMarmara University, Faculty of Medicine, Medical Microbiology, Istanbul, TurkeyMarmara University, Faculty of Medicine, Infectious Disease and Clinical Microbiology, Istanbul, TurkeyCryptococcus neoformans is generally observed with immunosuppressive conditions. Rarely, it may be seen in immunocompetent individuals and presented with non-specific conditions. We described an immunocompetent case of cryptococcal meningitis presented with multiple cerebral infarcts. Despite the late diagnosis and emergence of hydrocephalus during treatment, the patient was recovered without any sequelae. In immunocompetent patients, the conventional diagnostics tests may be negative because of the low fungal load. If it is available, the Biofire FilmArray meningitis panel has high sensitivity and specificity for diagnosis.http://www.sciencedirect.com/science/article/pii/S2214250921001104Cerebral infarctCryptococcus neoformansFilm arrayHydrocephalus
spellingShingle Buket Erturk Sengel
Elif Tukenmez Tigen
Rabia Can Sarinoglu
Ipek Midi
Nilgun Cerikcioglu
Zekaver Odabasi
Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient
IDCases
Cerebral infarct
Cryptococcus neoformans
Film array
Hydrocephalus
title Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient
title_full Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient
title_fullStr Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient
title_full_unstemmed Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient
title_short Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient
title_sort cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient
topic Cerebral infarct
Cryptococcus neoformans
Film array
Hydrocephalus
url http://www.sciencedirect.com/science/article/pii/S2214250921001104
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AT rabiacansarinoglu cryptococcusmeningitispresentedwithmultiplecerebralinfarctsinanimmunocompetentpatient
AT ipekmidi cryptococcusmeningitispresentedwithmultiplecerebralinfarctsinanimmunocompetentpatient
AT nilguncerikcioglu cryptococcusmeningitispresentedwithmultiplecerebralinfarctsinanimmunocompetentpatient
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