Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes

Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes

Nearly all mitochondrial proteins need to be targeted for import from the cytosol. For the majority, the first port of call is the translocase of the outer membrane (TOM complex), followed by a procession of alternative molecular machines, conducting transport to their final destination. The pre-seq...

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Bibliographic Details
Main Authors: Holly C Ford, William J Allen, Gonçalo C Pereira, Xia Liu, Mark Simon Dillingham, Ian Collinson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
mitochondria
import
kinetics
protein transport
Online Access:https://elifesciences.org/articles/75426

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