2'-Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine

2'-Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine

Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used against HIV-1. Currently, NVP is the most widely used anti-HIV drug in developing countries, both in combination therapy and to prevent mother-to-child transmission of HIV. Despite its efficacy against HIV, NVP produce...

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Bibliographic Details
Main Authors: M. Matilde Marques, Frederick A. Beland, M. Conceição Oliveira, Benjamin Wolf, Alexandra M. M. Antunes
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Molecules
Subjects:
nevirapine
non-nucleoside reverse transcriptase inhibitor
carcinogenicity
DNA adducts
palladium catalysis
Online Access:http://www.mdpi.com/1420-3049/18/5/4955

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