The Purinome and the preBötzinger Complex – A Ménage of Unexplored Mechanisms That May Modulate/Shape the Hypoxic Ventilatory Response

The Purinome and the preBötzinger Complex – A Ménage of Unexplored Mechanisms That May Modulate/Shape the Hypoxic Ventilatory Response

Exploration of purinergic signaling in brainstem homeostatic control processes is challenging the traditional view that the biphasic hypoxic ventilatory response, which comprises a rapid initial increase in breathing followed by a slower secondary depression, reflects the interaction between periphe...

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Bibliographic Details
Main Authors: Robert J. Reklow, Tucaaue S. Alvares, Yong Zhang, Ana P. Miranda Tapia, Vivian Biancardi, Alexis K. Katzell, Sara M. Frangos, Megan A. Hansen, Alexander W. Toohey, Carol E. Cass, James D. Young, Silvia Pagliardini, Detlev Boison, Gregory D. Funk
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
hypoxia
P2 receptor
P1 receptor
ectonucleotidase
equilibrative nucleoside transporter
adenosine kinase
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00365/full

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