“Block and attack” strategy for tumor therapy through ZnO2/siRNA/NIR‐mediating Zn2+‐overload and amplified oxidative stress

Abstract Intracellular zinc ion (Zn2+) accumulation disrupts the Zn2+ homeostasis, providing an ion‐overloading anticancer strategy with great potential. The self‐adaptation of tumor cells to ion concentration, however, puts forward higher requirements for the design of ion‐overloading strategy. Her...

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Bibliographic Details
Main Authors: Yuping Jiang, Kai Shao, Fenglan Zhang, Tianyi Wang, Lei Han, Xiaoying Kong, Jinsheng Shi
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Aggregate
Subjects:
Online Access:https://doi.org/10.1002/agt2.321