Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails
Being the primary sulfonamide among the most efficient zinc binding group (ZBG) to design inhibitors for the metallo-enzymes carbonic anhydrases (CA, EC 4.2.1.1), herein, we propose an investigation on four physiologically important human (h) CAs (hCA I, II, IV, and IX) with N1-substituted secondary...
| Автори: | , , , , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Taylor & Francis Group
2018-01-01
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| Серія: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Предмети: | |
| Онлайн доступ: | http://dx.doi.org/10.1080/14756366.2018.1446432 |