Small Changes in Inter-Pulse-Intervals Can Cause Synchronized Neuronal Firing During High-Frequency Stimulations in Rat Hippocampus

Small Changes in Inter-Pulse-Intervals Can Cause Synchronized Neuronal Firing During High-Frequency Stimulations in Rat Hippocampus

Deep brain stimulation (DBS) traditionally utilizes electrical pulse sequences with a constant frequency, i.e., constant inter-pulse-interval (IPI), to treat certain brain disorders in clinic. Stimulation sequences with varying frequency have been investigated recently to improve the efficacy of exi...

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Bibliographic Details
Main Authors: Zhouyan Feng, Weijian Ma, Zhaoxiang Wang, Chen Qiu, Hanhan Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Neuroscience
Subjects:
high-frequency stimulation
temporal patterns
population spike
synchronous firing
axonal stimulation
hippocampal CA1 region
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00036/full

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