T cells of colorectal cancer patients’ stimulated by neoantigenic and cryptic peptides better recognize autologous tumor cells

T cells of colorectal cancer patients’ stimulated by neoantigenic and cryptic peptides better recognize autologous tumor cells

Background Patients with cancers that exhibit extraordinarily high somatic mutation numbers are ideal candidates for immunotherapy and enable identifying tumor-specific peptides through stimulation of tumor-reactive T cells (Tc).Methods Colorectal cancers (CRC) HROC113 and HROC285 were selected base...

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Bibliographic Details
Main Authors: Peter Bauer, Hans-Georg Rammensee, Nadine Mockel-Tenbrinck, Andrzej Dzionek, Andreas Schlosser, Michael Ghosh, Markus W Löffler, Sandra Schwarz, Johanna Schmitz, Evgenia Olshvang, Marvin Markel, Susann Krake, Basak Arslan, Kapil Dev Kampe, Anne Wendt, Christina S Mullins, Michael Linnebacher
Format: Article
Language:English
Published: BMJ Publishing Group 2022-12-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/12/e005651.full

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