Prognosis for ocular toxocariasis according to granuloma location.
PURPOSE:To determine the prognosis for ocular toxocariasis (OT) according to the location of the granuloma and to identify factors associated with its recurrence within 1 year. METHODS:OT patients were classified according to the granuloma lesion. After grouping the patients as posterior or peripher...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC6117002?pdf=render |
| _version_ | 1819012833329807360 |
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| author | Jin-Woo Kwon Sun Young Lee Donghyun Jee Yang Kyung Cho |
| author_facet | Jin-Woo Kwon Sun Young Lee Donghyun Jee Yang Kyung Cho |
| author_sort | Jin-Woo Kwon |
| collection | DOAJ |
| description | PURPOSE:To determine the prognosis for ocular toxocariasis (OT) according to the location of the granuloma and to identify factors associated with its recurrence within 1 year. METHODS:OT patients were classified according to the granuloma lesion. After grouping the patients as posterior or peripheral, we compared sex, age, intraocular pressure, best corrected visual acuity (BCVA), degree of inflammation, immunoglobulin E, eosinophil profiles, recurrence, and complications in each group. We also identified factors associated with recurrence within 1 year. RESULTS:A total of 29 (61.70%) patients had granuloma at the periphery, and 18 (38.30%) patients had granuloma around the posterior pole. There were no significant differences in ocular or systemic evaluations except the initial BCVA. The mean decimal BCVA of the posterior pole granuloma group was worse than that of the peripheral granuloma group (p = 0.042). After treatment, the mean BCVA of the posterior pole granuloma group improved significantly (p = 0.019), and the final mean BCVA was not significantly different between the groups (p = 0.673). Multiple logistic regression analyses revealed that recurrence within a year was associated with age at diagnosis (p = 0.007). CONCLUSIONS:The initial BCVA of OT patients differed according to the location of the granuloma, but the BCVA after treatment was not significantly different between the groups. Younger age was associated with recurrence within 1 year. |
| first_indexed | 2024-12-21T01:50:20Z |
| format | Article |
| id | doaj.art-e445c7d7119e4462a82b3d13431dbf68 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-21T01:50:20Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-e445c7d7119e4462a82b3d13431dbf682022-12-21T19:19:55ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01138e020290410.1371/journal.pone.0202904Prognosis for ocular toxocariasis according to granuloma location.Jin-Woo KwonSun Young LeeDonghyun JeeYang Kyung ChoPURPOSE:To determine the prognosis for ocular toxocariasis (OT) according to the location of the granuloma and to identify factors associated with its recurrence within 1 year. METHODS:OT patients were classified according to the granuloma lesion. After grouping the patients as posterior or peripheral, we compared sex, age, intraocular pressure, best corrected visual acuity (BCVA), degree of inflammation, immunoglobulin E, eosinophil profiles, recurrence, and complications in each group. We also identified factors associated with recurrence within 1 year. RESULTS:A total of 29 (61.70%) patients had granuloma at the periphery, and 18 (38.30%) patients had granuloma around the posterior pole. There were no significant differences in ocular or systemic evaluations except the initial BCVA. The mean decimal BCVA of the posterior pole granuloma group was worse than that of the peripheral granuloma group (p = 0.042). After treatment, the mean BCVA of the posterior pole granuloma group improved significantly (p = 0.019), and the final mean BCVA was not significantly different between the groups (p = 0.673). Multiple logistic regression analyses revealed that recurrence within a year was associated with age at diagnosis (p = 0.007). CONCLUSIONS:The initial BCVA of OT patients differed according to the location of the granuloma, but the BCVA after treatment was not significantly different between the groups. Younger age was associated with recurrence within 1 year.http://europepmc.org/articles/PMC6117002?pdf=render |
| spellingShingle | Jin-Woo Kwon Sun Young Lee Donghyun Jee Yang Kyung Cho Prognosis for ocular toxocariasis according to granuloma location. PLoS ONE |
| title | Prognosis for ocular toxocariasis according to granuloma location. |
| title_full | Prognosis for ocular toxocariasis according to granuloma location. |
| title_fullStr | Prognosis for ocular toxocariasis according to granuloma location. |
| title_full_unstemmed | Prognosis for ocular toxocariasis according to granuloma location. |
| title_short | Prognosis for ocular toxocariasis according to granuloma location. |
| title_sort | prognosis for ocular toxocariasis according to granuloma location |
| url | http://europepmc.org/articles/PMC6117002?pdf=render |
| work_keys_str_mv | AT jinwookwon prognosisforoculartoxocariasisaccordingtogranulomalocation AT sunyounglee prognosisforoculartoxocariasisaccordingtogranulomalocation AT donghyunjee prognosisforoculartoxocariasisaccordingtogranulomalocation AT yangkyungcho prognosisforoculartoxocariasisaccordingtogranulomalocation |