Statistical inference and reverse engineering of gene regulatory networks from observational expression data.
In this paper, we present a systematic and conceptual overview of methods for inferring gene regulatory networks from observational gene expression data. Further, we discuss two classic approaches to infer causal structures and compare them with contemporary methods by providing a conceptual categor...
Main Authors: | Frank eEmmert-Streib, Galina eGlazko, Altay eG¨okmen, Ricardo eDe Matos Simoes |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-02-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00008/full |
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