FT- SERS Study of Adriamycin - DNA Intraction

FT-SERS (Fourier Transform Surface Enhanced Raman Scattering) of adriamycin and its complex with DNA is reported. It is shown that in agreement with previous Raman studies the interaction of adriamycin  with DNA takes place through an intercalation mechanism. The presence of a new band at 731 cm-1 s...

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Main Author: Amanollah Aminzadeh
Format: Article
Language:English
Published: Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR 2003-04-01
Series:Iranian Journal of Chemistry & Chemical Engineering
Subjects:
Online Access:http://www.ijcce.ac.ir/article_8182_d9a65a0c544c252a25fe2d8816c121e1.pdf
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author Amanollah Aminzadeh
author_facet Amanollah Aminzadeh
author_sort Amanollah Aminzadeh
collection DOAJ
description FT-SERS (Fourier Transform Surface Enhanced Raman Scattering) of adriamycin and its complex with DNA is reported. It is shown that in agreement with previous Raman studies the interaction of adriamycin  with DNA takes place through an intercalation mechanism. The presence of a new band at 731 cm-1 suggests that ring D of adriamycin is not involved in the intercalation process.
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spelling doaj.art-e4472ad32c7a4b72bb8e8d9bd51c00e82022-12-22T00:56:06ZengIranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECRIranian Journal of Chemistry & Chemical Engineering1021-99861021-99862003-04-012219118182FT- SERS Study of Adriamycin - DNA IntractionAmanollah Aminzadeh0College of Chemistry, Isfahan University of echnology, Isfahan 84154, I. R. IranFT-SERS (Fourier Transform Surface Enhanced Raman Scattering) of adriamycin and its complex with DNA is reported. It is shown that in agreement with previous Raman studies the interaction of adriamycin  with DNA takes place through an intercalation mechanism. The presence of a new band at 731 cm-1 suggests that ring D of adriamycin is not involved in the intercalation process.http://www.ijcce.ac.ir/article_8182_d9a65a0c544c252a25fe2d8816c121e1.pdfft-sersadriamycindnamedical researchantitumor activity
spellingShingle Amanollah Aminzadeh
FT- SERS Study of Adriamycin - DNA Intraction
Iranian Journal of Chemistry & Chemical Engineering
ft-sers
adriamycin
dna
medical research
antitumor activity
title FT- SERS Study of Adriamycin - DNA Intraction
title_full FT- SERS Study of Adriamycin - DNA Intraction
title_fullStr FT- SERS Study of Adriamycin - DNA Intraction
title_full_unstemmed FT- SERS Study of Adriamycin - DNA Intraction
title_short FT- SERS Study of Adriamycin - DNA Intraction
title_sort ft sers study of adriamycin dna intraction
topic ft-sers
adriamycin
dna
medical research
antitumor activity
url http://www.ijcce.ac.ir/article_8182_d9a65a0c544c252a25fe2d8816c121e1.pdf
work_keys_str_mv AT amanollahaminzadeh ftsersstudyofadriamycindnaintraction