Erucin inhibits osteoclast formation via suppressing cell–cell fusion molecule DC-STAMP without influencing mineralization by osteoblasts

Erucin inhibits osteoclast formation via suppressing cell–cell fusion molecule DC-STAMP without influencing mineralization by osteoblasts

Abstract Objective Erucin (ERN), an isothiocyanate, is derived from the vegetable arugula. Although ERN has antitumor and antioxidant activity, the effect of ERN on osteoclast and osteoblast differentiation is not well documented. In this study, we evaluated the effects of ERN on osteoclast and oste...

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Bibliographic Details
Main Authors: Tomohiro Takagi, Hirofumi Inoue, Shungo Fujii, Nobuyuki Takahashi, Mariko Uehara
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Research Notes
Subjects:
Erucin
Isothiocyanate
Osteoclast differentiation
Osteoclast cell fusion
DC-STAMP
Online Access:https://doi.org/10.1186/s13104-022-05988-3

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