Sonographic Decreased Echogenicity of Thyroid Parenchyma in Asymptomatic Population: Correlation with Thyroid Function and Thyroid Autoimmune Activity
Purpose The aim of the study was to evaluate the correlation between decreased echogenicity of thyroid and thyroid hormones or autoantibodies. Materials and Methods From January 2009 to December 2011, 543 patients with decreased parenchymal echogenicity [M:F = 133:410, median age: 42 years (ran...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Radiology
2016-09-01
|
| Series: | 대한영상의학회지 |
| Subjects: | |
| Online Access: | https://doi.org/10.3348/jksr.2016.75.3.177 |
| _version_ | 1818957860438016000 |
|---|---|
| author | Ji Yeon Park Noh Hyuck Park Chan Sub Park Ji Ye Lee Kyung Ah Chun Seong Yoon Yi Hee Jin Park |
| author_facet | Ji Yeon Park Noh Hyuck Park Chan Sub Park Ji Ye Lee Kyung Ah Chun Seong Yoon Yi Hee Jin Park |
| author_sort | Ji Yeon Park |
| collection | DOAJ |
| description | Purpose
The aim of the study was to evaluate the correlation between decreased echogenicity of thyroid and thyroid hormones or autoantibodies.
Materials and Methods
From January 2009 to December 2011, 543 patients with decreased parenchymal echogenicity [M:F = 133:410, median age: 42 years (range: 9–82 years)], who did not have solid nodule, symptom or medication related to thyroid and underwent thyroid function test were retrospectively reviewed. Images were classified based on the degree of hypoechogenicity, heterogenicity or thyroid size. 1) Group A: mild decreased echogenicity, group B: marked decreased echogenicity, 2) group Ho: homogeneous echogenicity, group He: heterogeneous echogenicity, 3) group 1: decreased size, group 2: normal size, group 3: increased size. Differences in triiodiothyronyne (T3), free-thyroxine (fT4), thyrotropin (TSH), anti-thyroglobulin antibody (TgAb), thyroid peroxidase antibody (TPOAb), and anti-TSH receptor antibody (TSH-rAb) were evaluated among groups.
Results
T3, fT4, and TSH levels differed between groups A and B (p < 0.001, p = 0.001, p < 0.001). TgAb and TPOAb of group B were higher than group A (p = 0.006, p < 0.001). TPOAb of group He was higher than group Ho (p < 0.001). TSH-rAb and TPOAb of group 3 were higher than group 2 (p = 0.017, p < 0.001).
Conclusion
The patients with findings of markedly decreased, heterogeneous echogenicity or thyroid enlargement may have abnormal thyroid function and autoantibodies. These may facilitate the physicians' decision to order tests for thyroid function and autoimmune activity. |
| first_indexed | 2024-12-20T11:16:34Z |
| format | Article |
| id | doaj.art-e4492cf94a7c4698bb8f564d509e2013 |
| institution | Directory Open Access Journal |
| issn | 1738-2637 2288-2928 |
| language | English |
| last_indexed | 2024-12-20T11:16:34Z |
| publishDate | 2016-09-01 |
| publisher | The Korean Society of Radiology |
| record_format | Article |
| series | 대한영상의학회지 |
| spelling | doaj.art-e4492cf94a7c4698bb8f564d509e20132022-12-21T19:42:37ZengThe Korean Society of Radiology대한영상의학회지1738-26372288-29282016-09-01753177184https://doi.org/10.3348/jksr.2016.75.3.177Sonographic Decreased Echogenicity of Thyroid Parenchyma in Asymptomatic Population: Correlation with Thyroid Function and Thyroid Autoimmune ActivityJi Yeon Park0Noh Hyuck Park1Chan Sub Park2Ji Ye Lee3Kyung Ah Chun4Seong Yoon Yi5Hee Jin Park6Department of Radiology, Myongji Hospital, Seonam University College of Medicine, Goyang, KoreaDepartment of Radiology, Myongji Hospital, Seonam University College of Medicine, Goyang, KoreaDepartment of Radiology, Myongji Hospital, Seonam University College of Medicine, Goyang, KoreaDepartment of Radiology, Myongji Hospital, Seonam University College of Medicine, Goyang, KoreaDepartment of Radiology, Catholic Kwandong University School of Medicine, Gangneung, KoreaDivision of Hematology-Oncology, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, KoreaDepartment of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, KoreaPurpose The aim of the study was to evaluate the correlation between decreased echogenicity of thyroid and thyroid hormones or autoantibodies. Materials and Methods From January 2009 to December 2011, 543 patients with decreased parenchymal echogenicity [M:F = 133:410, median age: 42 years (range: 9–82 years)], who did not have solid nodule, symptom or medication related to thyroid and underwent thyroid function test were retrospectively reviewed. Images were classified based on the degree of hypoechogenicity, heterogenicity or thyroid size. 1) Group A: mild decreased echogenicity, group B: marked decreased echogenicity, 2) group Ho: homogeneous echogenicity, group He: heterogeneous echogenicity, 3) group 1: decreased size, group 2: normal size, group 3: increased size. Differences in triiodiothyronyne (T3), free-thyroxine (fT4), thyrotropin (TSH), anti-thyroglobulin antibody (TgAb), thyroid peroxidase antibody (TPOAb), and anti-TSH receptor antibody (TSH-rAb) were evaluated among groups. Results T3, fT4, and TSH levels differed between groups A and B (p < 0.001, p = 0.001, p < 0.001). TgAb and TPOAb of group B were higher than group A (p = 0.006, p < 0.001). TPOAb of group He was higher than group Ho (p < 0.001). TSH-rAb and TPOAb of group 3 were higher than group 2 (p = 0.017, p < 0.001). Conclusion The patients with findings of markedly decreased, heterogeneous echogenicity or thyroid enlargement may have abnormal thyroid function and autoantibodies. These may facilitate the physicians' decision to order tests for thyroid function and autoimmune activity.https://doi.org/10.3348/jksr.2016.75.3.177thyroid glandultrasonographythyroid hormonesautoantibodies |
| spellingShingle | Ji Yeon Park Noh Hyuck Park Chan Sub Park Ji Ye Lee Kyung Ah Chun Seong Yoon Yi Hee Jin Park Sonographic Decreased Echogenicity of Thyroid Parenchyma in Asymptomatic Population: Correlation with Thyroid Function and Thyroid Autoimmune Activity 대한영상의학회지 thyroid gland ultrasonography thyroid hormones autoantibodies |
| title | Sonographic Decreased Echogenicity of Thyroid Parenchyma in Asymptomatic Population: Correlation with Thyroid Function and Thyroid Autoimmune Activity |
| title_full | Sonographic Decreased Echogenicity of Thyroid Parenchyma in Asymptomatic Population: Correlation with Thyroid Function and Thyroid Autoimmune Activity |
| title_fullStr | Sonographic Decreased Echogenicity of Thyroid Parenchyma in Asymptomatic Population: Correlation with Thyroid Function and Thyroid Autoimmune Activity |
| title_full_unstemmed | Sonographic Decreased Echogenicity of Thyroid Parenchyma in Asymptomatic Population: Correlation with Thyroid Function and Thyroid Autoimmune Activity |
| title_short | Sonographic Decreased Echogenicity of Thyroid Parenchyma in Asymptomatic Population: Correlation with Thyroid Function and Thyroid Autoimmune Activity |
| title_sort | sonographic decreased echogenicity of thyroid parenchyma in asymptomatic population correlation with thyroid function and thyroid autoimmune activity |
| topic | thyroid gland ultrasonography thyroid hormones autoantibodies |
| url | https://doi.org/10.3348/jksr.2016.75.3.177 |
| work_keys_str_mv | AT jiyeonpark sonographicdecreasedechogenicityofthyroidparenchymainasymptomaticpopulationcorrelationwiththyroidfunctionandthyroidautoimmuneactivity AT nohhyuckpark sonographicdecreasedechogenicityofthyroidparenchymainasymptomaticpopulationcorrelationwiththyroidfunctionandthyroidautoimmuneactivity AT chansubpark sonographicdecreasedechogenicityofthyroidparenchymainasymptomaticpopulationcorrelationwiththyroidfunctionandthyroidautoimmuneactivity AT jiyelee sonographicdecreasedechogenicityofthyroidparenchymainasymptomaticpopulationcorrelationwiththyroidfunctionandthyroidautoimmuneactivity AT kyungahchun sonographicdecreasedechogenicityofthyroidparenchymainasymptomaticpopulationcorrelationwiththyroidfunctionandthyroidautoimmuneactivity AT seongyoonyi sonographicdecreasedechogenicityofthyroidparenchymainasymptomaticpopulationcorrelationwiththyroidfunctionandthyroidautoimmuneactivity AT heejinpark sonographicdecreasedechogenicityofthyroidparenchymainasymptomaticpopulationcorrelationwiththyroidfunctionandthyroidautoimmuneactivity |