3-(3-Bromophenyl)-7-acetoxycoumarin

In natural product synthesis, the procurement of easily accessible starting materials is crucial. Chromenones and their subclass, coumarins, are a wide family of small, oxygen-containing aromatic heterocycles. Phenylcoumarins offer a particularly excellent starting point for a diverse chemical space...

Full description

Bibliographic Details
Main Authors: Petri A. Turhanen, Liisa P. Nousiainen, Juri M. Timonen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2022/4/M1513
Description
Summary:In natural product synthesis, the procurement of easily accessible starting materials is crucial. Chromenones and their subclass, coumarins, are a wide family of small, oxygen-containing aromatic heterocycles. Phenylcoumarins offer a particularly excellent starting point for a diverse chemical space of natural products, and thus are excellent staring materials for more complex natural products. Herein, we report an efficient synthesis of an easily accessible 3-phenylcoumarin bearing two orthogonally substitutable groups, bromine, and an acetyl-protected phenylic hydroxyl group.
ISSN:1422-8599