Effects of AgRP inhibition on energy balance and metabolism in rodent models.

Effects of AgRP inhibition on energy balance and metabolism in rodent models.

Activation of brain melanocortin-4 receptors (MC4-R) by α-melanocyte-stimulating hormone (MSH) or inhibition by agouti-related protein (AgRP) regulates food intake and energy expenditure and can modulate neuroendocrine responses to changes in energy balance. To examine the effects of AgRP inhibition...

Full description

Bibliographic Details
Main Authors:	Roxanne Dutia, Andrea J Kim, Matthew Modes, Robert Rothlein, Jane M Shen, Ye Edward Tian, Jumana Ihbais, Sam F Victory, Carmen Valcarce, Sharon L Wardlaw
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3675096?pdf=render

Similar Items

Ghrelin signalling in AgRP neurons links metabolic state to the sensory regulation of AgRP neural activity
by: Wang Lok So, et al.
Published: (2023-12-01)

p53 and energy balance: meeting hypothalamic AgRP neurons
by: Omar Al-Massadi, et al.
Published: (2018-10-01)

AgRP Neurons Regulate Bone Mass
by: Jae Geun Kim, et al.
Published: (2015-10-01)

AgRP Accountants Compute Caloric Cost
by: Jing Liang, et al.
Published: (2017-12-01)

Identification of AgRP cells in the murine hindbrain that drive feeding
by: Tomas P. Bachor, et al.
Published: (2024-02-01)

Drp1 is required for AgRP neuronal activity and feeding
by: Sungho Jin, et al.
Published: (2021-03-01)

Heparin Increases Food Intake through AgRP Neurons
by: Canjun Zhu, et al.
Published: (2017-09-01)

Ablation of AgRP neurons impairs adaption to restricted feeding
by: Keith Tan, et al.
Published: (2014-10-01)

Opioidergic signaling contributes to food-mediated suppression of AgRP neurons
by: Nilufer Sayar-Atasoy, et al.
Published: (2024-01-01)

Sustained inhibition of NPY/AgRP neuronal activity by FGF1
by: Eunsang Hwang, et al.
Published: (2022-09-01)

AgRP neurons are not indispensable for body weight maintenance in adult mice
by: Jing Cai, et al.
Published: (2023-07-01)

Sustained NPY signaling enables AgRP neurons to drive feeding
by: Yiming Chen, et al.
Published: (2019-04-01)

Cold-induced hyperphagia requires AgRP neuron activation in mice
by: Jennifer D Deem, et al.
Published: (2020-12-01)

Correction: Drp1 is required for AgRP neuronal activity and feeding
by: Sungho Jin, et al.
Published: (2022-06-01)

PGC-1α expression in murine AgRP neurons regulates food intake and energy balance
by: Jonathan F. Gill, et al.
Published: (2016-07-01)

microRNA-33 controls hunger signaling in hypothalamic AgRP neurons
by: Nathan L. Price, et al.
Published: (2024-03-01)

Malocclusion impairs cognitive behavior via AgRP signaling in adolescent mice
by: Junya Kusumoto, et al.
Published: (2023-04-01)

Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin
by: Lars Paeger, et al.
Published: (2017-06-01)

Dieting reverses histone methylation and hypothalamic AgRP regulation in obese rats
by: Kayla Rapps, et al.
Published: (2023-02-01)

AgRP neurons trigger long-term potentiation and facilitate food seeking
by: Chunmei Wang, et al.
Published: (2021-01-01)

DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice
by: Harry MacKay, et al.
Published: (2019-12-01)

Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons
by: Isadora C. Furigo, et al.
Published: (2019-02-01)

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.
by: Könner, A, et al.
Published: (2007)

Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake
by: Carolyn M. Lorch, et al.
Published: (2024-02-01)

Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
by: Yi Zhang, et al.
Published: (2024-03-01)

Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum
by: Alex Reichenbach, et al.
Published: (2022-01-01)

Obesity causes selective and long-lasting desensitization of AgRP neurons to dietary fat
by: Lisa R Beutler, et al.
Published: (2020-07-01)

Local Drd1-neurons input to subgroups of arcuate AgRP/NPY-neurons
by: Sean R. Chadwick, et al.
Published: (2022-07-01)

Somato-dendritic localization and signaling by leptin receptors in hypothalamic POMC and AgRP neurons.
by: Sangdeuk Ha, et al.
Published: (2013-01-01)

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
by: Bora Lee, et al.
Published: (2018-05-01)

The Ghrelin-AgRP Neuron Nexus in Anorexia Nervosa: Implications for Metabolic and Behavioral Adaptations
by: Mathieu Méquinion, et al.
Published: (2020-01-01)

Cellular and synaptic reorganization of arcuate NPY/AgRP and POMC neurons after exercise
by: Zhenyan He, et al.
Published: (2018-12-01)

AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning
by: Alex Reichenbach, et al.
Published: (2018-02-01)

CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst
by: Sebastián Zagmutt, et al.
Published: (2023-03-01)

CRISPR knockdown of Kcnq3 attenuates the M-current and increases excitability of NPY/AgRP neurons to alter energy balance
by: Todd L. Stincic, et al.
Published: (2021-07-01)

Anti-inflammatory effects of hunger are transmitted to the periphery via projection-specific AgRP circuits
by: Michelle L. Klima, et al.
Published: (2023-11-01)

Acute inhibition of hunger-sensing AgRP neurons promotes context-specific learning in mice
by: Felicia Reed, et al.
Published: (2023-11-01)

Effects of Thymoquinone on Hypothalamic NPY and AgRP Gene Expression in Intact and Hypothyroidism- Model Rats
by: Nasrin Ghahremani, et al.
Published: (2022-07-01)

Inhibition of c-Jun in AgRP neurons increases stress-induced anxiety and colitis susceptibility
by: Fuxin Jiao, et al.
Published: (2023-01-01)

Correction: Somato-Dendritic Localization and Signaling by Leptin Receptors in Hypothalamic POMC and AgRP Neurons
Published: (2013-01-01)