What Can We Learn from FGF-2 Isoform-Specific Mouse Mutants? Differential Insights into FGF-2 Physiology In Vivo

What Can We Learn from FGF-2 Isoform-Specific Mouse Mutants? Differential Insights into FGF-2 Physiology In Vivo

Fibroblast growth factor 2 (FGF-2), ubiquitously expressed in humans and mice, is functionally involved in cell growth, migration and maturation in vitro and in vivo. Based on the same mRNA, an 18-kilo Dalton (kDa) FGF-2 isoform named FGF-2 low molecular weight (FGF-2LMW) isoform is translated in hu...

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Bibliographic Details
Main Authors: Friederike Freiin von Hövel, Ekaterini Kefalakes, Claudia Grothe
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
FGF-2ko
FGF-2LMWko
FGF-2HMWko
FGF-2LMWtg
FGF-2HMWtg
mutant mice
Online Access:https://www.mdpi.com/1422-0067/22/1/390

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