Evaluation of a new fusion antigen, cd loop and HAP2-GCS1 domain (cd-HAP) of Plasmodium falciparum Generative Cell Specific 1 antigen formulated with various adjuvants, as a transmission blocking vaccine

Evaluation of a new fusion antigen, cd loop and HAP2-GCS1 domain (cd-HAP) of Plasmodium falciparum Generative Cell Specific 1 antigen formulated with various adjuvants, as a transmission blocking vaccine

Abstract Background Malaria is a major global health challenge, and for the elimination and eradication of this disease, transmission-blocking vaccines (TBVs) are a priority. Plasmodium falciparum Generative Cell Specific 1 (PfGCS1), a promising TBV candidate, is essential for gamete fertilization....

Full description

Bibliographic Details
Main Authors: Zeinab Pourhashem, Leila Nourani, Jafar J. Sani, Hemn Yousefi, Sakineh Pirahmadi, Mobina Sabouri, Abbasali Raz, Navid Dinparast Djadid, Sedigheh Zakeri, Akram Abouie Mehrizi
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Malaria Journal
Subjects:
Malaria vaccine
Cd-HAP antigen
Adjuvants
Immunogenicity
SMFA
Naturally acquired antibodies
Online Access:https://doi.org/10.1186/s12936-023-04798-7

Similar Items

Similar Items