Evaluation of Selected Properties of Sodium Alginate-Based Hydrogel Material—Mechanical Strength, μDIC Analysis and Degradation

The search for ideal solutions for the treatment of urethral stenosis continues. This includes developing the material, design, while maintaining its optimal and desired properties. This paper presents the results of the research conducted on sodium alginate-based hydrogel material (AHM), which may...

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Main Authors: Jagoda Kurowiak, Agnieszka Mackiewicz, Tomasz Klekiel, Romuald Będziński
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/15/3/1225
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author Jagoda Kurowiak
Agnieszka Mackiewicz
Tomasz Klekiel
Romuald Będziński
author_facet Jagoda Kurowiak
Agnieszka Mackiewicz
Tomasz Klekiel
Romuald Będziński
author_sort Jagoda Kurowiak
collection DOAJ
description The search for ideal solutions for the treatment of urethral stenosis continues. This includes developing the material, design, while maintaining its optimal and desired properties. This paper presents the results of the research conducted on sodium alginate-based hydrogel material (AHM), which may be used as a material for stents dedicated to the treatment of pathologies occurring in the genitourinary system. In order to determine the selected parameters of the AHM samples, strength and degradation tests, as well as analysis of the micro changes occurring on the surface of the material using a digital image correlation (µDIC) system, were performed. This study shows that the material possessed good mechanical strength parameters, the knowledge of which is particularly important from the point of view of the stent-tissue interaction. The degradation analysis performed showed that the AHM samples degrade in an artificial urine environment, and that the degradation time mainly depends on the chemical composition of the material. The novel µDIC method performed allowed us to characterize the homogeneity of the material structure depending on the cross-linking agent used.
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spelling doaj.art-e45d30806d6f48e5a3d1363a9ae90e962023-11-23T17:04:22ZengMDPI AGMaterials1996-19442022-02-01153122510.3390/ma15031225Evaluation of Selected Properties of Sodium Alginate-Based Hydrogel Material—Mechanical Strength, μDIC Analysis and DegradationJagoda Kurowiak0Agnieszka Mackiewicz1Tomasz Klekiel2Romuald Będziński3Department of Biomedical Engineering, Institute of Material and Biomedical Engineering, Faculty of Mechanical Engineering, University of Zielona Góra, Licealna 9 Street, 65-417 Zielona Góra, PolandDepartment of Biomedical Engineering, Institute of Material and Biomedical Engineering, Faculty of Mechanical Engineering, University of Zielona Góra, Licealna 9 Street, 65-417 Zielona Góra, PolandDepartment of Biomedical Engineering, Institute of Material and Biomedical Engineering, Faculty of Mechanical Engineering, University of Zielona Góra, Licealna 9 Street, 65-417 Zielona Góra, PolandDepartment of Biomedical Engineering, Institute of Material and Biomedical Engineering, Faculty of Mechanical Engineering, University of Zielona Góra, Licealna 9 Street, 65-417 Zielona Góra, PolandThe search for ideal solutions for the treatment of urethral stenosis continues. This includes developing the material, design, while maintaining its optimal and desired properties. This paper presents the results of the research conducted on sodium alginate-based hydrogel material (AHM), which may be used as a material for stents dedicated to the treatment of pathologies occurring in the genitourinary system. In order to determine the selected parameters of the AHM samples, strength and degradation tests, as well as analysis of the micro changes occurring on the surface of the material using a digital image correlation (µDIC) system, were performed. This study shows that the material possessed good mechanical strength parameters, the knowledge of which is particularly important from the point of view of the stent-tissue interaction. The degradation analysis performed showed that the AHM samples degrade in an artificial urine environment, and that the degradation time mainly depends on the chemical composition of the material. The novel µDIC method performed allowed us to characterize the homogeneity of the material structure depending on the cross-linking agent used.https://www.mdpi.com/1996-1944/15/3/1225sodium alginatehydrogelsstentsurologydigital image correlation
spellingShingle Jagoda Kurowiak
Agnieszka Mackiewicz
Tomasz Klekiel
Romuald Będziński
Evaluation of Selected Properties of Sodium Alginate-Based Hydrogel Material—Mechanical Strength, μDIC Analysis and Degradation
Materials
sodium alginate
hydrogels
stents
urology
digital image correlation
title Evaluation of Selected Properties of Sodium Alginate-Based Hydrogel Material—Mechanical Strength, μDIC Analysis and Degradation
title_full Evaluation of Selected Properties of Sodium Alginate-Based Hydrogel Material—Mechanical Strength, μDIC Analysis and Degradation
title_fullStr Evaluation of Selected Properties of Sodium Alginate-Based Hydrogel Material—Mechanical Strength, μDIC Analysis and Degradation
title_full_unstemmed Evaluation of Selected Properties of Sodium Alginate-Based Hydrogel Material—Mechanical Strength, μDIC Analysis and Degradation
title_short Evaluation of Selected Properties of Sodium Alginate-Based Hydrogel Material—Mechanical Strength, μDIC Analysis and Degradation
title_sort evaluation of selected properties of sodium alginate based hydrogel material mechanical strength μdic analysis and degradation
topic sodium alginate
hydrogels
stents
urology
digital image correlation
url https://www.mdpi.com/1996-1944/15/3/1225
work_keys_str_mv AT jagodakurowiak evaluationofselectedpropertiesofsodiumalginatebasedhydrogelmaterialmechanicalstrengthmdicanalysisanddegradation
AT agnieszkamackiewicz evaluationofselectedpropertiesofsodiumalginatebasedhydrogelmaterialmechanicalstrengthmdicanalysisanddegradation
AT tomaszklekiel evaluationofselectedpropertiesofsodiumalginatebasedhydrogelmaterialmechanicalstrengthmdicanalysisanddegradation
AT romualdbedzinski evaluationofselectedpropertiesofsodiumalginatebasedhydrogelmaterialmechanicalstrengthmdicanalysisanddegradation