Evaluation of Effects of Zingiber officinale on Salivation in Rats
There are some herbal plants in Iranian traditional system of medicine which are believed to be excellent remedies to alleviate the symptoms of xerostomia. The aim of the present study was to evaluate the effect of systemic administration of seven different herbal extracts on the rate of salivation...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2011-06-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/3753 |
| _version_ | 1811333227633180672 |
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| author | Goli Chamani Mohammad Reza Zarei Mitra Mehrabani Yousef Taghiabadi |
| author_facet | Goli Chamani Mohammad Reza Zarei Mitra Mehrabani Yousef Taghiabadi |
| author_sort | Goli Chamani |
| collection | DOAJ |
| description | There are some herbal plants in Iranian traditional system of medicine which are believed to be excellent remedies to alleviate the symptoms of xerostomia. The aim of the present study was to evaluate the effect of systemic administration of seven different herbal extracts on the rate of salivation in rats. The extracts of 7 herbs; Zingiber officinale Roscoe (Zingiberaceae), Citrus sinensis (L.) Osbeck (Rutaceae), Artemisia absinthium L. (Asteraceae), Cichorium intybus L. (Asteraceae), Pimpinella anisum L.(Apiaceae), Portulaca oleracea L.(Portulacaceae), Tribulus terrestris L. (Zygophyllaceae) were prepared. Nine groups of animals (including negative and positive control groups) were used and seven rats were tested in each group. After the injection of extracts, saliva volume was measured gravimetrically in four continuous sevenminute intervals. The results showed that after injection of ginger extracts salivation was significantly higher as compared to the negative control group and other herbal extracts in all of the four intervals (P<0.01). The peak action of the ginger was during the first 7-minute interval and following this, salivation decreased to some extent. The present study suggests that the extract of Zingiber offiicianle can increase the rate of salivation significantly in animal model. Further investigations on different constituents of ginger seem to be essential to identify the responsible constituent for stimulation of saliva secretion. |
| first_indexed | 2024-04-13T16:49:44Z |
| format | Article |
| id | doaj.art-e46a9ace0a844a91bda6a9cf08cb8a40 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-04-13T16:49:44Z |
| publishDate | 2011-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-e46a9ace0a844a91bda6a9cf08cb8a402022-12-22T02:38:59ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942011-06-01496Evaluation of Effects of Zingiber officinale on Salivation in RatsGoli Chamani0Mohammad Reza Zarei1Mitra Mehrabani2Yousef Taghiabadi3Department of Oral Medicine, Kerman School of Dentistry, Kerman, Iran.Kerman Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran.Department of Pharmacognosy, School of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.Private Practice, Kerman, Iran.There are some herbal plants in Iranian traditional system of medicine which are believed to be excellent remedies to alleviate the symptoms of xerostomia. The aim of the present study was to evaluate the effect of systemic administration of seven different herbal extracts on the rate of salivation in rats. The extracts of 7 herbs; Zingiber officinale Roscoe (Zingiberaceae), Citrus sinensis (L.) Osbeck (Rutaceae), Artemisia absinthium L. (Asteraceae), Cichorium intybus L. (Asteraceae), Pimpinella anisum L.(Apiaceae), Portulaca oleracea L.(Portulacaceae), Tribulus terrestris L. (Zygophyllaceae) were prepared. Nine groups of animals (including negative and positive control groups) were used and seven rats were tested in each group. After the injection of extracts, saliva volume was measured gravimetrically in four continuous sevenminute intervals. The results showed that after injection of ginger extracts salivation was significantly higher as compared to the negative control group and other herbal extracts in all of the four intervals (P<0.01). The peak action of the ginger was during the first 7-minute interval and following this, salivation decreased to some extent. The present study suggests that the extract of Zingiber offiicianle can increase the rate of salivation significantly in animal model. Further investigations on different constituents of ginger seem to be essential to identify the responsible constituent for stimulation of saliva secretion.https://acta.tums.ac.ir/index.php/acta/article/view/3753Herbal medicineSalivationXerostomia |
| spellingShingle | Goli Chamani Mohammad Reza Zarei Mitra Mehrabani Yousef Taghiabadi Evaluation of Effects of Zingiber officinale on Salivation in Rats Acta Medica Iranica Herbal medicine Salivation Xerostomia |
| title | Evaluation of Effects of Zingiber officinale on Salivation in Rats |
| title_full | Evaluation of Effects of Zingiber officinale on Salivation in Rats |
| title_fullStr | Evaluation of Effects of Zingiber officinale on Salivation in Rats |
| title_full_unstemmed | Evaluation of Effects of Zingiber officinale on Salivation in Rats |
| title_short | Evaluation of Effects of Zingiber officinale on Salivation in Rats |
| title_sort | evaluation of effects of zingiber officinale on salivation in rats |
| topic | Herbal medicine Salivation Xerostomia |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/3753 |
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