Detection of Cerebrovascular Disease in a Child with Hutchinson-Gilford Progeria Syndrome Using MR Angiography: A Case Report
Hutchinson-Gilford progeria syndrome (HGPS) is a rare, progressive, premature aging syndrome with early morbidity due to cardiovascular and cerebrovascular diseases. Clinical symptoms are very diverse, including non-specific symptoms such as growth retardation, scleroderma, alopecia, and osteoporo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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The Korean Society of Radiology
2022-11-01
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| Series: | 대한영상의학회지 |
| Online Access: | https://doi.org/10.3348/jksr.2022.0051 |
| _version_ | 1798016157567942656 |
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| author | Jae Ho Lee Ha Young Lee Myung Kwan Lim Young Hye Kang |
| author_facet | Jae Ho Lee Ha Young Lee Myung Kwan Lim Young Hye Kang |
| author_sort | Jae Ho Lee |
| collection | DOAJ |
| description | Hutchinson-Gilford progeria syndrome (HGPS) is a rare, progressive, premature aging syndrome with
early morbidity due to cardiovascular and cerebrovascular diseases. Clinical symptoms are very diverse,
including non-specific symptoms such as growth retardation, scleroderma, alopecia, and osteoporosis,
as well as hypertension and cardiovascular diseases that occur in childhood and adolescence
due to accelerated vascular aging. In patients with HGPS, MR angiography is recommended for
early diagnosis of asymptomatic stroke or vascular changes and to assess increased risk of cerebrovascular
disease. We report the second domestic case of HGPS confirmed by genetic analysis in a
5-year-old child with typical clinical features, and the first English case report in Korea to present
brain MR angiography findings. |
| first_indexed | 2024-04-11T15:46:17Z |
| format | Article |
| id | doaj.art-e46b3fd4d50c4dfca9d5f1e2bb855508 |
| institution | Directory Open Access Journal |
| issn | 2288-2928 |
| language | English |
| last_indexed | 2024-04-11T15:46:17Z |
| publishDate | 2022-11-01 |
| publisher | The Korean Society of Radiology |
| record_format | Article |
| series | 대한영상의학회지 |
| spelling | doaj.art-e46b3fd4d50c4dfca9d5f1e2bb8555082022-12-22T04:15:35ZengThe Korean Society of Radiology대한영상의학회지2288-29282022-11-0183613601365Detection of Cerebrovascular Disease in a Child with Hutchinson-Gilford Progeria Syndrome Using MR Angiography: A Case ReportJae Ho LeeHa Young LeeMyung Kwan LimYoung Hye KangHutchinson-Gilford progeria syndrome (HGPS) is a rare, progressive, premature aging syndrome with early morbidity due to cardiovascular and cerebrovascular diseases. Clinical symptoms are very diverse, including non-specific symptoms such as growth retardation, scleroderma, alopecia, and osteoporosis, as well as hypertension and cardiovascular diseases that occur in childhood and adolescence due to accelerated vascular aging. In patients with HGPS, MR angiography is recommended for early diagnosis of asymptomatic stroke or vascular changes and to assess increased risk of cerebrovascular disease. We report the second domestic case of HGPS confirmed by genetic analysis in a 5-year-old child with typical clinical features, and the first English case report in Korea to present brain MR angiography findings.https://doi.org/10.3348/jksr.2022.0051 |
| spellingShingle | Jae Ho Lee Ha Young Lee Myung Kwan Lim Young Hye Kang Detection of Cerebrovascular Disease in a Child with Hutchinson-Gilford Progeria Syndrome Using MR Angiography: A Case Report 대한영상의학회지 |
| title | Detection of Cerebrovascular Disease in a Child with Hutchinson-Gilford Progeria Syndrome Using MR Angiography: A Case Report |
| title_full | Detection of Cerebrovascular Disease in a Child with Hutchinson-Gilford Progeria Syndrome Using MR Angiography: A Case Report |
| title_fullStr | Detection of Cerebrovascular Disease in a Child with Hutchinson-Gilford Progeria Syndrome Using MR Angiography: A Case Report |
| title_full_unstemmed | Detection of Cerebrovascular Disease in a Child with Hutchinson-Gilford Progeria Syndrome Using MR Angiography: A Case Report |
| title_short | Detection of Cerebrovascular Disease in a Child with Hutchinson-Gilford Progeria Syndrome Using MR Angiography: A Case Report |
| title_sort | detection of cerebrovascular disease in a child with hutchinson gilford progeria syndrome using mr angiography a case report |
| url | https://doi.org/10.3348/jksr.2022.0051 |
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