Clinical and pharmacological aspects of using hormone-like effects of micronutrients during menopause

Estrogen deficiency is the main cause of menopausal symptoms of varying intensity. Administration of vitamin and mineral supplements is a part of nonhormonal drug therapy and an etiopathologically substantiated method of therapy. Improving energy supply in cells and increasing the level of cyclic ad...

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Main Authors: E. V. Shikh, A. A. Makhova
Format: Article
Language:Russian
Published: Remedium Group LLC 2016-12-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/43
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author E. V. Shikh
A. A. Makhova
author_facet E. V. Shikh
A. A. Makhova
author_sort E. V. Shikh
collection DOAJ
description Estrogen deficiency is the main cause of menopausal symptoms of varying intensity. Administration of vitamin and mineral supplements is a part of nonhormonal drug therapy and an etiopathologically substantiated method of therapy. Improving energy supply in cells and increasing the level of cyclic adenosine monophosphate (cAMP) can alter receptor sensitivity and amplify expression of estrogen effects without increasing their synthesis. Vitamins A and D affect gene transcription resulting in changes in synthesis of proteins which realize various biological potentials. The vast majority of women surveyed (70-80%) in the territory of the Russian Federation suffer from poly-hypovitaminoses, no matter their age, season, place of residence or professional affiliation. Additional supplementation with micronutrients has a positive effect on the body's defense system by stimulating non-specific resistance reactions, and that is key for the prevention of various diseases in the period of waning reproductive function.
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spelling doaj.art-e46f96ca724e4e67b77229cda216d27a2023-04-23T06:56:38ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902016-12-0102687310.21518/2079-701X-2016-2-68-7343Clinical and pharmacological aspects of using hormone-like effects of micronutrients during menopauseE. V. Shikh0A. A. Makhova1First Moscow State Medical University named after I.M. SechenovFirst Moscow State Medical University named after I.M. SechenovEstrogen deficiency is the main cause of menopausal symptoms of varying intensity. Administration of vitamin and mineral supplements is a part of nonhormonal drug therapy and an etiopathologically substantiated method of therapy. Improving energy supply in cells and increasing the level of cyclic adenosine monophosphate (cAMP) can alter receptor sensitivity and amplify expression of estrogen effects without increasing their synthesis. Vitamins A and D affect gene transcription resulting in changes in synthesis of proteins which realize various biological potentials. The vast majority of women surveyed (70-80%) in the territory of the Russian Federation suffer from poly-hypovitaminoses, no matter their age, season, place of residence or professional affiliation. Additional supplementation with micronutrients has a positive effect on the body's defense system by stimulating non-specific resistance reactions, and that is key for the prevention of various diseases in the period of waning reproductive function.https://www.med-sovet.pro/jour/article/view/43климактерический периодмикронутриентыгормоноподобные эффектыстероидные рецепторырегуляцияmenopausemicronutrientshormone-like effectssteroid receptorsregulation
spellingShingle E. V. Shikh
A. A. Makhova
Clinical and pharmacological aspects of using hormone-like effects of micronutrients during menopause
Медицинский совет
климактерический период
микронутриенты
гормоноподобные эффекты
стероидные рецепторы
регуляция
menopause
micronutrients
hormone-like effects
steroid receptors
regulation
title Clinical and pharmacological aspects of using hormone-like effects of micronutrients during menopause
title_full Clinical and pharmacological aspects of using hormone-like effects of micronutrients during menopause
title_fullStr Clinical and pharmacological aspects of using hormone-like effects of micronutrients during menopause
title_full_unstemmed Clinical and pharmacological aspects of using hormone-like effects of micronutrients during menopause
title_short Clinical and pharmacological aspects of using hormone-like effects of micronutrients during menopause
title_sort clinical and pharmacological aspects of using hormone like effects of micronutrients during menopause
topic климактерический период
микронутриенты
гормоноподобные эффекты
стероидные рецепторы
регуляция
menopause
micronutrients
hormone-like effects
steroid receptors
regulation
url https://www.med-sovet.pro/jour/article/view/43
work_keys_str_mv AT evshikh clinicalandpharmacologicalaspectsofusinghormonelikeeffectsofmicronutrientsduringmenopause
AT aamakhova clinicalandpharmacologicalaspectsofusinghormonelikeeffectsofmicronutrientsduringmenopause