Catalase Overexpression Drives an Aggressive Phenotype in Glioblastoma

Catalase Overexpression Drives an Aggressive Phenotype in Glioblastoma

Glioblastoma remains the deadliest form of brain cancer, largely because these tumors become resistant to standard of care treatment with radiation and chemotherapy. Intracellular production of reactive oxygen species (ROS) is necessary for chemo- and radiotherapy-induced cytotoxicity. Here, we asse...

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Bibliographic Details
Main Authors: Susanne Flor, Claudia R. Oliva, Md Yousuf Ali, Kristen L. Coleman, Jeremy D. Greenlee, Karra A. Jones, Varun Monga, Corinne E. Griguer
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Antioxidants
Subjects:
catalase
glioblastoma multiforme
reactive oxygen species (ROS)
hydrogen peroxide
radiation
temozolomide
Online Access:https://www.mdpi.com/2076-3921/10/12/1988

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