Discovery of novel conjugates of quinoline and thiazolidinone urea as potential anti-colorectal cancer agent

Discovery of novel conjugates of quinoline and thiazolidinone urea as potential anti-colorectal cancer agent

Based on the obtained SARs, further structural optimisation of compound BC2021-104511-15i was conducted in this investigation, and totally ten novel quinoline derivates were designed, synthesised and optimised for biological activity. Among them, compound 10a displayed significant in vitro anticance...

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Bibliographic Details
Main Authors:	Li Xiong, Huan He, Mengmeng Fan, Liping Hu, Fei Wang, Xiaomeng Song, Shengmin Shi, Baohui Qi
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2022-12-01
Series:	Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:	Anticancer HGFR MST1R quinoline structure modification
Online Access:	https://www.tandfonline.com/doi/10.1080/14756366.2022.2117318

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