Dissecting the cytomegalovirus CC chemokine: Chemokine activity and gHgLchemokine-dependent cell tropism are independent players in CMV infection.

Dissecting the cytomegalovirus CC chemokine: Chemokine activity and gHgLchemokine-dependent cell tropism are independent players in CMV infection.

Like all herpesviruses, cytomegaloviruses (CMVs) code for many immunomodulatory proteins including chemokines. The human cytomegalovirus (HCMV) CC chemokine pUL128 has a dual role in the infection cycle. On one hand, it forms the pentameric receptor-binding complex gHgLpUL(128,130,131A), which is cr...

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Bibliographic Details
Main Authors: Marwa Eletreby, Lena Thiessen, Adrian Prager, Ilija Brizic, Jelena Materljan, Lucie Kubic, Katharina Jäger, Križan Jurinović, Josipa Jerak, Karsten Krey, Barbara Adler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011793&type=printable

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