Acetylsalicylic acid reduces cigarette smoke withdrawal-induced anxiety in rats via modulating the expression of NFĸB, GLT-1, and xCT

Acetylsalicylic acid reduces cigarette smoke withdrawal-induced anxiety in rats via modulating the expression of NFĸB, GLT-1, and xCT

Background: Chronic exposure to cigarette smoke produces neuroinflammation and long-term changes in neurotransmitter systems, especially glutamatergic systems.Objective: We examined the effects of cigarette smoke on astroglial glutamate transporters as well as NF-κB expression in mesocorticolimbic b...

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Bibliographic Details
Main Authors: Alaa M. Hammad, Lujain F. Alzaghari, Malek Alfaraj, Walid Al-Qerem, Wamidh H. Talib, Fawaz Alasmari, Haneen Amawi, F. Scott Hall
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
GLT-1
XCT
NFkB
anxiety-like behavior
acetylsalicylic acid
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1047236/full

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