Is Elevation of Alkaline Phosphatase a Predictive Factor of Response to Alectinib in NSCLC?
In the following report, we describe a case of alkaline phosphatase (ALP) elevation occurring during treatment with alectinib (Alecensa™), which was administered for anaplastic lymphoma kinase (ALK) mutated metastatic non-small cell lung cancer (mNSCLC). A 51 year-old female with widespread metastat...
Main Authors: | Walid Shalata, Alexander Yakobson, Rachel Steckbeck, Ashraf Abu Jama, Omar Abu Saleh, Abed Agbarya |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
|
Series: | Current Oncology |
Subjects: | |
Online Access: | https://www.mdpi.com/1718-7729/29/1/16 |
Similar Items
-
Efficacy and Safety of Dose-Escalated Alectinib in Patients With Metastatic ALK-Positive NSCLC and Central Nervous System Relapse on Standard-Dose Alectinib
by: Justin M. Cheung, MD, et al.
Published: (2024-03-01) -
Alectinib and lorlatinib function by modulating EMT-related proteins and MMPs in NSCLC metastasis
by: Xu Feng, et al.
Published: (2021-06-01) -
Clinical case of prolonged use of alectinib in the treatment of ALK-positive NSCLC
by: S. G. Bagrova, et al.
Published: (2019-12-01) -
Sensitive Fluorescence Assay for the Detection of Alkaline Phosphatase Based on a Cu<sup>2+</sup>-Thiamine System
by: Han Zhao, et al.
Published: (2021-01-01) -
Alkaline phosphatase interference in immuno-enzymatic assays
by: Oğuz Osman, et al.
Published: (2022-01-01)