Cyclic AMP mediates ovine cumulus–oocyte gap junctional function via balancing connexin 43 expression and phosphorylation

Cyclic AMP mediates ovine cumulus–oocyte gap junctional function via balancing connexin 43 expression and phosphorylation

Gap junction channels in cumulus–oocyte complexes (COCs) enable the transmission and communication of small molecular signals between adjacent cells, such as cAMP. However, the regulation of gap junction function (GJF) by cAMP and the underlying mechanisms involved are not fully clarified. This stud...

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Bibliographic Details
Main Authors: Yufen Zhao, Erge Namei, Bingxue Yang, Xiangnan Bao, Wei Sun, Gerile Subudeng, Guifang Cao, Haijun Li, Gui Wang
Format: Article
Language:English
Published: Bioscientifica 2023-10-01
Series:Endocrine Connections
Subjects:
ovine cumulus–oocyte complexes
cyclic adenosine monophosphate
connexin 43
protein phosphorylation
gap junctional function
Online Access:https://ec.bioscientifica.com/view/journals/ec/12/11/EC-23-0337.xml

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